by PMI Science | 23 Dec 2016
During the design and the assessment processes of reduced-risk products, we get a very important indication about the potential of our novel heated tobacco products when we compare those to a so-called reference cigarette in the laboratory. As part of this comparison, we collected and analyzed what would be directly inhaled (as known as “mainstream”) by the future consumers of Platform 1 of our product portfolio. Platform 1 heats a tobacco-based plug, called a “heatstick”, to a temperature that creates an aerosol, which then reaches the lungs of the consumers. It does not generate smoke since no burning takes place.
The aerosol from the heatsticks was collected by a machine that imitates puffing. Similarly, cigarette smoke was collected from the filter side of the cigarette in a smoking machine. The smoke and the aerosol were channeled towards a pad that collected the particles of each sample.
The difference is clearly visible: while Platform 1 only slightly colored the pad while cigarette smoke turned it into dark brown because of the components of cigarette smoke. A thorough chemical analysis showed that Platform 1’s aerosol is mainly composed of water, glycerin and nicotine. The rest of the compounds only cover a small portion of the mainstream aerosol, while with cigarette smoke, more than half of the mass is different from water, glycerin or nicotine. The analyses also confirm that the level of harmful and potentially harmful compounds were on average 90-95% reduced in Platform 1’s aerosol compared to cigarette smoke.
For the results and the details of these analyses, please read the following peer-reviewed publication:
Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol
Following this chemical assessment step, a series of toxicological and clinical studies have also been performed on Platform 1, of which you can find plenty of information under this link:
Our Scientific Approach
You can see how such experiments are performed in our video: