Smoke-Free Products – The Scientific Update 03

by PMI Science | 02 November 2017

PMI releases its latest Scientific Update for Smoke-Free Products, a regular publication on its research efforts to develop and assess a range of potentially reduced-risk alternatives to cigarettes.

A downloadable PDF version of this update can be found by clicking on this link.

This issue of the Scientific Update focuses on PMI’s scientific assessment program as it applies to its Electronically Heated Tobacco Product (EHTP), referred to in the literature as the tobacco heating system (THS). PMI established its multi-step assessment program applying internationally accepted scientific and quality standards along the same principles as the US Food and Drug Administration (FDA) draft guidance (2012). The feature article outlines each step of the assessment program and summarizes key results of supporting data. Included is an overview of the more than 30 EHTP-related studies. PMI submitted this evidence to the FDA in the form of a modified risk tobacco product (MRTP) application.

Prof. Manuel Peitsch, PMI’s Chief Scientific Officer, explains: “We developed a truly world class R&D program to scientifically assess the potential of our smoke-free products to reduce risk. With each progressive step of our assessment of EHTP, we have seen a significant reduction in exposure to a number of harmful chemicals and risk potential compared with cigarettes. Because transparency is a vital part of our program, we are making our evidence available for others to review.”

Beyond the MRTP-related content, the Scientific Update provides an overview of the assessment to date on its smoke-free product portfolio. It also covers key presentations at scientific conferences.

An important factor of this update is to complement our ongoing efforts to share our latest science. We encourage those who are interested in learning more to explore this website, and follow us on social media platforms @pmiscience.

You can also read our first and second Scientific Update Issues.