The Smoke Science & Product Technology conference will have 71 oral presentations that will occur across nine “live” on-line sessions between 18-28 October. In addition, there will be seven presentations given in the Symposium on “Advancing New Alternative Methods (NAMs) for Tobacco Harm Reduction”. The technical program includes an array of presentations covering numerous topics, such as perception and behavior, nicotine science, analytical methods, product chemistry, biomarkers, statistical modeling, and in vitro & in vivo toxicology. Science associated with conventional tobacco products such as combustible cigarettes and emerging tobacco products including e-vapor products, heated tobacco products (HTP), nicotine pouches, and waterpipes, will be presented. Each presentation is pre-recorded, with a “live” question and answer session after each presentation.