Toxicological Assessment

      Regulatory Toxicology

      Regulatory Toxicology focuses on assessing the toxicity of our products on cells grown in the laboratory and in laboratory animals.

      The main purpose of Regulatory Toxicology is to provide data for regulatory agencies on whether our products meet their defined acceptability criteria. These criteria include requirements for manufacturing and clinical tests. In the case of smoke-free tobacco products, the aim is to demonstrate that the toxicity of the aerosol from smoke free products is lower than that of cigarettes.

      Regulatory Toxicology assessment is performed under Good Laboratory Practice (GLP). GLP ensures uniformity, consistency, reliability, reproducibility, quality and integrity in the methodology of the tests and hence the results.

      Read about our Regulatory Toxicology assays

      Read our Regulatory Toxicology papers and presentations

      Our findings and related articles

      PMIScience.com is operated by Philip Morris International for the purpose of publishing and disseminating scientific information about Philip Morris International’s efforts to develop and assess products that have the potential to reduce individual risk and population harm associated with tobacco use. This site is for use by scientists, the public health and regulatory communities, and other stakeholders with an interest in tobacco policy. The purpose of this site is not for advertising or marketing. It is not intended for use by consumers.

      Reduced Risk Products ("RRPs”) is the term we use to refer to products that present, are likely to present, or have the potential to present less risk of harm to smokers who switch to these products versus continuing smoking. PMI has a range of RRPs in various stages of development, scientific assessment and commercialization. Our RRPs are smoke-free products that produce an aerosol that contains far lower quantities of harmful and potentially harmful constituents than found in cigarette smoke.