Supported Investigator Initiated Studies | PMI Science

These are the supported studies so far:

IIS number	Investigator/Sponsor	Institution	Study title	Start/end dates	Type of study	Type of support	Amount of support
IIS.PMI. 2016.1	Dr. Almaz Sharman	Academy of Preventive Medicine	Cross-sectional study of COPD and smoking	July 25th, 2016 to March 31st, 2018	Clinical	Financial Equipment	KZT 300,112,769 KZT 5,102,442
IIS.PMI. 2016.1	Dr. Almaz Sharman	Academy of Preventive Medicine	A 5-year cohort observational study to evaluate frequency of exacerbations, respiratory symptoms, physical exercise intolerance and abnormal lung functions among participants who use IQOS with heatsticks compared to smokers of conventional cigarettes	October 23rd 2017 to June 1st 2024	Clinical	Financial Technical	KZT 2,479,470,618 + IQOS User Database
IIS.PMI. 2017.16	Dr. Violeta Kauneliene	Kaunas University of Technology	Research on the Effects of Exhaled Pollutants from Tobacco Heating System (THS) on Indoor Air Quality	September 18th 2017 to October 2nd 2018	Aerosol Chemistry	Financial (including product costs) Technical	EUR 102,265 Nicotine method demonstration
IIS.PMI.2016.4	Dr Enrico Mondati*	University of Catania	A 12-weeks open label, non-inferiority trial comparing HnB products vs ECs in terms of efficacy and adoption rates, acceptability, tolerability, and tobacco harm reduction in healthy smokers, not motivated to quit.	December 20th, 2017 to October 30th, 2019	Clinical	Financial (including product costs) & Technical	EUR 968,708
IIS.PMI. 2016.1	Dr. Almaz Sharman	Academy of Preventive Medicine	A Proof-of-concept, Open-label, Three-arm Study to Evaluate Mobile Applications and Biosensing (mHealth) Devices to Monitor Physical Activity, Respiratory Function, and Antioxidant Capacity in Smokers with and without Respiratory Symptoms/COPD	April 9th, 2018 to August 20th, 2019	Clinical	Financial	KZT 136,428,759
IIS.PMI.2017.30	Professor Elefteria Psillakis	Technical University of Crete	Leaching of chemicals of environmental concern from used heated tobacco sticks to natural water and comparison with leaching from smoked conventional cigarettes	June 1st, 2018 to June 2020	Environmental Impact	Financial & Material	EUR 99’533

* The study was initiated by Professor Riccardo Polosa. PMI consented to change principal investigator on the 31st of March 2018 and the necessary approvals were obtained on the 30th of July 2018.

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Reduced Risk Products (“RRPs”) is the term we use to refer to products that present, are likely to present, or have the potential to present less risk of harm to smokers who switch to these products versus continuing smoking. PMI has a range of RRPs in various stages of development, scientific assessment and commercialization. Our RRPs are smoke-free products that produce an aerosol that contains far lower quantities of harmful and potentially harmful constituents than found in cigarette smoke.