Analysis of propylene oxide in THS aerosol

Authored by  PMI

The aerosols are generated on a linear smoking machine and collected using Cambridge filter pad (CFP) followed by two impingers filled with 5 mL of toluene. After the smoking process, the CFP is discarded and the contents of the two impingers are combined and delivered to the analytical laboratory for addition of internal standard and analysis.

The extracts are analyzed by Gas Chromatography with Mass Spectrometry detection (GC-MS) using a column Agilent Pora Bond Q 25 m x 0.25 mm ID x 3 µm film thickness.

Results are expressed as µg/item for P1.