Analysis of Glycerin and Menthol in THS aerosol

Authored by  PMI

The aerosol samples are generated by mean of a 20 port linear smoking machine. The mainstream aerosol is collected on a 44mm Cambridge filter pad (CFP).
Glycerin trapped in the CFP is extracted using an in-situ approach and menthol compound using a non in-situ approach. In both the cases, the target compound is extracted with isopropanol containing internal standards (ISTDs), n-heptadecane and ethanol.
The extracts are analyzed by Gas Chromatography (GC) with Flame Ionization Detector (FID). The GC system is equipped with a column RTx-35 30 m x 0.25 mm ID x 1 μm film thickness.
Results are expressed as mg/item for Platform 1.