Peer-Reviewed Publication
Full Title
In Vivo Assessment Of Emphysema In Mice By High Resolution X-Ray Microtomography
Authored by
AA Postnov*, K Meurrens, H Weiler, D Van Dyck, H Xu, P Terpstra, NM De Clerck*
Published in The Journal of Microscopy
* This author is not affiliated with PMI.
Published in The Journal of Microscopy
* This author is not affiliated with PMI.
Abstract
High resolution X-ray microtomography (micro-CT) was used for the detection of emphysema in live mice. Emphysema was induced in c57Bl/6 J mice by intratracheal instillation of different amounts of porcine pancreatic elastase. This emphysema could be clearly detected by micro-CT seven weeks post-treatment: Analysis of the whole data set of virtual cross-sections showed the presence of a dose-dependent level of emphysema.
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Published On
November 2, 2005 -
Full publication
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DOI
10.1111/j.1365-2818.2005.01510.x -
PMID: 16269065