Nicotine Pharmacokinetic Profile and Safety of the Tobacco Heating System 2.2 Menthol (THS 2.2 Menthol)

A Single-center, Open-label, Randomized, Controlled, Crossover Study to Investigate the Nicotine Pharmacokinetic Profile and Safety of Tobacco Heating System 2.2 Menthol (THS 2.2 Menthol) Following Single Use in Smoking, Healthy Subjects Compared to Menthol Conventional Cigarettes and Nicotine Gum.


Authored by  PMI

The primary objective of this clinical study is to evaluate the pharmacokinetic (PK) profile (rate and amount of nicotine absorbed) following a single use of the THS 2.2 Menthol (mTHS) compared to the PK profiles from a single use of a menthol conventional cigarette (mCC) and from a single use of nicotine replacement therapy gum (NRT).

Recruitment Completed
Study Results Has Results
Enrollment 73
Study Type Interventional
Other IDs ZRHM-PK-05-JP