Pharmacokinetics Of Nicotine And Subjective Effects Following The Single Use Of A Non-Menthol And Menthol Version Of Tobacco Heating System 2.2 In Two Studies In Japan: A Comparison With Single Use Of A Combustible Cigarette And Nicotine Gum

Authored by  P Picavet, C Haziza, G Baker, N Lama, J Ancerewicz, M Benzimra, F Nobuoka*, M Sugimoto*, F L├╝dicke

Presented at SRNT 2015 21st Annual Meeting     
* This author is not affiliated with PMI.


The two studies discussed here are part of a clinical program to assess the Tobacco Heating System 2.2 (THS 2.2), a candidate modified risk tobacco product. The objective of the studies was to evaluate the pharmacokinetic (PK) profile of nicotine following single use of THS 2.2 non-menthol and menthol as compared to combustible cigarettes (CC) and nicotine gum.