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Pharmacokinetics Of Nicotine And Subjective Effects Following The Single Use Of A Non-Menthol And Menthol Version Of Tobacco Heating System 2.2 In Two Studies In Japan: A Comparison With Single Use Of A Combustible Cigarette And Nicotine Gum


Authored by  P Picavet, C Haziza, G Baker, N Lama, J Ancerewicz, M Benzimra, F Nobuoka*, M Sugimoto*, F Lüdicke

Presented at SRNT 2015 21st Annual Meeting     
* This author is not affiliated with PMI.

Abstract

The two studies discussed here are part of a clinical program to assess the Tobacco Heating System 2.2 (THS 2.2), a candidate modified risk tobacco product. The objective of the studies was to evaluate the pharmacokinetic (PK) profile of nicotine following single use of THS 2.2 non-menthol and menthol as compared to combustible cigarettes (CC) and nicotine gum.

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Our RRPs

Reduced-risk products ("RRPs") is the term we use to refer to products that present, are likely to present, or have the potential to present less risk of harm to smokers who switch to these products versus continued smoking. We have a range of RRPs in various stages of development, scientific assessment and commercialization. Because our RRPs do not burn tobacco, they produce an aerosol that contains far lower quantities of harmful and potentially harmful constituents than found in cigarette smoke.