About Guillaume
I am responsible for the statistical design and evaluation of several Reduced-Risk Products (RRPs) in clinical and post-marketing studies, contributing to discussions with different authorities for the best statistical methodologies to apply.
Latest Publications
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Peer-Reviewed Publication
May 6, 2020
Heated Tobacco Products
Exposure to harmful and potentially harmful constituents decreased in smokers switching to Carbon-Heated Tobacco Product
M Bosilkovska, CT Tran, G de La Bourdonnaye, BV Taranu, M Benzimra, C Haziza
DOI : 10.1016/j.toxlet.2020.04.013
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Publication
May 24, 2019
Heated Tobacco Products
Favorable Changes in Biomarkers of Potential Harm to Reduce the Adverse Health Effects of Smoking in Smokers Switching to the Menthol Tobacco Heating System 2.2 for Three Months (Part 2)
C Haziza, G de La Bourdonnaye, A Donelli, D Skiada, V Poux, R Weitkunat, G Baker, P Picavet, F Lüdicke
DOI : 10.1093/ntr/ntx028
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Poster
March 12, 2019
Heated Tobacco Products
Xenobiotic metabolism response to 3R4F or THS2.2 exposure: from pre-clinical to clinical
S Pouly, M Talikka, A van der Plas, B Titz, A Iskandar, G de La Bourdonnaye, N Blanc, F Martin, C Haziza, NV Ivanov, F Lüdicke, J Hoeng, M Peitsch
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Poster
February 22, 2019
Platform 1
Cardiovascular Effects Observed When Using the Tobacco Heating System (THS) Compared with Continued Smoking
C Pater, C Haziza, A Elamin, M S Ansari, S Pouly, G de La Bourdonnaye, CT Tran, F Lüdicke
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Poster
February 22, 2019
Platform 2
Decreased Levels of Biomarkers of Exposure in Smokers Switching to Carbon-Heated Tobacco Product 1.2 compared with those who continued to smoke: A Randomized, Controlled, Open-Label 90-Day Exposure Study
CT Tran, M Bosilkovska, G de La Bourdonnaye, N Blanc, M Benzimra, J Ancerewicz, C Haziza, F Lüdicke
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Poster
February 18, 2019
Platform 1
Assessing the Impact of Switching to the Tobacco Heating System on Cardiovascular Events: Translating Basic Science into Clinical Benefit
C Pater, C Haziza, A Elamin, S Pouly, G de La Bourdonnaye, CT Tran, F Lüdicke
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Peer-Reviewed Publication
February 5, 2019
Platform 1
Reduction In Exposure To Selected Harmful And Potentially Harmful Constituents Approaching Those Observed Upon Smoking Abstinence In Smokers Switching To The Menthol Tobacco Heating System 2.2 For Three Months (Part 1)
C Haziza, G de La Bourdonnaye, A Donelli, V Poux, D Skiada, R Weitkunat, G Baker, P Picavet, F Lüdicke
DOI : 10.1093/ntr/ntz013
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Peer-Reviewed Publication
November 19, 2018
Influence of smoking on levels of urinary 8-iso Prostaglandin F2α
A van der Plas, S Pouly, G de La Bourdonnaye, G Baker, F Lüdicke
DOI : 10.1016/j.toxrep.2018.11.011
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Poster
October 8, 2018
Platform 1
Cardiovascular Effects Observed When Using the Tobacco Heating System (THS) 2.2 Compared with Continued Smoking
C Pater, C Haziza, A Elamin, S Pouly, G de La Bourdonnaye, CT Tran, F Lüdicke
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Peer-Reviewed Publication
April 19, 2018
Influence of smoking and smoking cessation on levels of urinary 11-dehydro thromboxane B2
A van der Plas, S Pouly, G de La Bourdonnaye, W Teck Ng, G Baker, F Lüdicke
DOI : 10.1016/j.toxrep.2018.04.005
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Peer-Reviewed Publication
December 29, 2017
Platform 1
Accuracy of the Smoking Questionnaire
Z Sponsiello Wang, G de La Bourdonnaye, M David, F Lüdicke, R Weitkunat
Beiträge zur Tabakforschung International/Contributions to Tobacco Research
DOI : 10.1515/cttr-2017-0023
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Poster
November 10, 2017
Platform 1
Measuring Changes in Patterns of Tobacco Product Use Over Time: Transition Probability Approaches
E. F. Afolalu, L Prieto, G de La Bourdonnaye, Z Sponsiello Wang, R Weitkunat
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Poster
September 14, 2017
Platform 2
Biomarker of Exposure Reductions Upon Switching for 5 Days From Cigarettes to a Carbon Heated Tobacco Product (CHTP 1.0)
C Tran, A Donelli, C Haziza, J Ancerewicz, G de La Bourdonnaye, R Weitkunat, F Lüdicke
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Infoposter
June 16, 2017
Platform 2
Biomarker of exposure reductions upon switching for 5 days from cigarettes to a carbon heated tobacco product (CHTP 1.0)
A Donelli, C Tran, C Haziza, J Ancerewicz, G de La Bourdonnaye, R Weitkunat, F Lüdicke
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Poster
March 10, 2017
Platform 2
Biomarker of Exposure Reductions Upon Switching for 5 Days from Cigarettes to a Carbon Heated Tobacco Product (CHTP 1.0)
A Donelli, C Tran, C Haziza, J Ancerewicz, G de La Bourdonnaye, R Weitkunat, F Lüdicke
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Publication
March 10, 2017
Biomarker of Exposure Reductions Upon Switching for five Days from Cigarettes to a Carbon Heated Tobacco Product (CHTP 1.0)
F Lüdicke, R Weitkunat, G de La Bourdonnaye, J Ancerewicz, C Haziza, C Tran, A Donelli
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Publication
February 1, 2017
Heated Tobacco Products
Biomarker of exposure level data set in smokers switching from conventional cigarettes to Tobacco Heating System 2.2, continuing smoking or abstaining from smoking for 5 days
C Haziza, G de La Bourdonnaye, D Skiada, J Ancerewicz, G Baker, P Picavet, F Lüdicke
DOI : 10.1016/j.dib.2016.11.047
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Peer-Reviewed Publication
January 4, 2017
Platform 1
Biomarker of exposure level data set in smokers switching from conventional cigarettes to Tobacco Heating System 2.2, continuing smoking or abstaining from smoking for 5 days
C Haziza, G de La Bourdonnaye, D Skiada, J Ancerewicz, G Baker, P Picavet, F Lüdicke
DOI : 10.1016/j.dib.2016.11.047
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Peer-Reviewed Publication
November 4, 2016
Platform 1
Evaluation of the Tobacco Heating System 2.2. Part 8: 5-Day randomized reduced exposure clinical study in Poland
C Haziza, G de La Bourdonnaye, D Skiada, J Ancerewicz, G Baker, P Picavet, F Lüdicke
Regulatory Toxicology and Pharmacology
DOI : 10.1016/j.yrtph.2016.11.003
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Peer-Reviewed Publication
September 29, 2016
Platform 1
Assessment of the reduction in levels of exposure to harmful and potentially harmful constituents in Japanese subjects using a novel tobacco heating system compared with conventional cigarettes and smoking abstinence: A randomized controlled study in confinement
C Haziza, G de La Bourdonnaye, S Merlet, M Benzimra, J Ancerewicz, A Donelli, G Baker, P Picavet, F Lüdicke
Regulatory Toxicology and Pharmacology
DOI : 10.1016/j.yrtph.2016.09.014
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Poster
June 24, 2016
Heated Tobacco Products
Accuracy of the Smoking Questionnaire (SQ)
Z Sponsiello Wang, G de La Bourdonnaye, M David, G Baker, F Lüdicke, R Weitkunat
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Poster
June 17, 2016
Heated Tobacco Products
Comparing The Levels Of Harmful Compounds In Smokers That Either Continue To Smoke, Quit Or Switch To THS2.2 Menthol (USA)
C Haziza, G de La Bourdonnaye, P Picavet, G Baker, D Skiada, S Merlet, M Franzon, F Farmer, W Lewis, F Lüdicke
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Poster
November 10, 2015
Heated Tobacco Products
Reduced exposure to harmful and potentially harmful constituents after 90 days of use of tobacco heating system 2.2 menthol in the U.S.: a comparison with continued cigarette use or smoking abstinence
C Haziza, G de La Bourdonnaye, P Picavet, G Baker, D Skiada, S Merlet, M Franzon, F Farmer, W Lewis, F Lüdicke
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Poster
March 23, 2015
Heated Tobacco Products
Reduced Exposure To Harmful And Potentially Harmful Constituents After Five Days of Use of Tobacco Heating System 2.2. A Comparison with Continued Combustible Cigarette Use or Smoking Abstinence [Poland]
C Haziza, G de La Bourdonnaye, P Picavet, G Baker, D Skiada, J Ancerewicz, K Jarus-Dziedzic*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Platform 1
Investigation on puffing topography parameters and product evaluation recorded during five days of use of the Tobacco Heating System 2.2: A comparison with continued combustible cigarette use
G de La Bourdonnaye, T Bachmann, C Haziza, P Picavet, G Baker, D Skiada, K Jarus-Dziedzic*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Heated Tobacco Products
Pharmacokinetics Of Nicotine And Subjective Effects Following The Single Use Of A Menthol Version Of Tobacco Heating System 2.2 In The US: A Comparison With Single Use Of A Combustible Cigarette And Nicotine Nasal Spray
C Haziza, G Baker, G de La Bourdonnaye, N Lama, J Ancerewicz, D Skiada, P Picavet, JL Borders*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Heated Tobacco Products
Reduced Exposure To Harmful And Potentially Harmful Constituents After Five Days Of Use Of tobacco Heating System 2.2: A Comparison With Continued Combustible Cigarette Use Or Smoking Abstinence [Japan]
C Haziza, G de La Bourdonnaye, G Baker, M Benzimra, J Ancerewicz, P Picavet, F Lüdicke
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Poster
June 20, 2014
Heated Tobacco Products
Association of urinary 11-dehydro-thromboxane b2 levels in smoking, smoking cessation and tobacco heating system use
A van der Plas, S Pouly, G de La Bourdonnaye, G Baker, F Lüdicke
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Poster
September 21, 2013
Quantification Of The Effect Of Smoking And Smoking Cessation On Lipid Parameters: A Meta-Analysis
A van der Plas, G de La Bourdonnaye, G Baker, R Weitkunat, F Lüdicke