About Patrick
I am leading the group that defines the clinical assessment strategy, scientifically oversees and conducts clinical research to scientifically substantiate the risk reduction potential of our candidate Reduced-Risk Products.
Latest Publications
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Report
December 10, 2018
Platform 1
Summary of Evidence: Cytotoxic Effects on Bronchial Epithelial Cells
G Baker, P Picavet, M Smith, P Vanscheeuwijck, E Veljkovic, M Peitsch
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Report
November 20, 2018
Platform 1
Summary of the Evidence: Pulmonary and Immunosuppressive Effects of IQOS
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Presentation
November 19, 2018
Platform 1
Respiratory Effects Observed When Using the Tobacco Heating System (THS) Compared with Continued Smoking
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Poster
September 17, 2018
Platform 1
Cardiovascular Effects Observed When Using the Tobacco Heating System (THS) 2.2 Compared with Continued Smoking
G Baker, C Haziza, J Hoeng, NV Ivanov, F Lüdicke, S Maeder, M Peitsch, B Phillips, P Picavet, C Poussin, P Vanscheeuwijck
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Peer-Reviewed Publication
August 24, 2018
Platform 1
Evaluation of Biological and Functional Changes in Healthy Smokers Switching to the Tobacco Heating System 2.2 Versus Continued Tobacco Smoking: Protocol for a Randomized, Controlled, Multicenter Study
M S Ansari, N Lama, N Blanc, M Bosilkovska, A Donelli, P Picavet, G Baker, C Haziza, F Lüdicke
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Infoposter
June 15, 2018
A Multi-Center, Multi-Regional, Study on Biological and Functional Changes in Healthy Adult Smokers during One Year of Continuous Smoking Abstinence
C Tran, Loyse Felber Medlin , N Lama, BV Taranu, E Pierri, J Ancerewicz, P Picavet, G Baker, C Haziza, F Lüdicke
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Infoposter
June 15, 2018
Evaluation of biological and functional changes in healthy smokers after switching from cigarettes to Tobacco Heating System (THS) 2.2 for 6 months
S Ansari, N Lama, N Blanc, D Skiada, J Ancerewicz, P Picavet, G Baker, C Haziza, F Lüdicke
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Poster
June 11, 2018
Platform 1
Cardiovascular Effects Observed When Using the Tobacco Heating System (THS) 2.2 Compared with Continued Smoking
G Baker, C Haziza, J Hoeng, NV Ivanov, F Lüdicke, S Maeder, M Peitsch, B Phillips, P Picavet, C Poussin, P Vanscheeuwijck
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Poster
June 11, 2018
Platform 1
Changes in Clinical Risk Endpoints Linked to Cardiovascular and Other Smoking-Related Diseases after Switching from Cigarettes to the Tobacco Heating System (THS) 2.2 for Six Months
C Haziza, S Ansari, N Lama, M Bosilkovska, N Blanc, D Skiada, J Ancerewicz, P Picavet, G Baker, F Lüdicke
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Poster
May 9, 2018
Human Research Investigation on the Effects of Cigarette Smoking, E-Cigarette Vaping, and Smoking Cessation on Vascular Cell Biology
C Poussin, J Hoeng, S Ansari, E Guedj, TM Curran*, LA Baglia*, RA Berg*, N Blumberg*, SL Spinelli*, Loyse Felber Medlin , NV Ivanov, P Picavet, M Peitsch
* This author is not affiliated with PMI. -
Poster
February 26, 2018
A multi-center multiregional study on biological and functional changes in healthy adult smokers during one year of continuous smoking abstinence
C Tran, Loyse Felber Medlin , N Lama, BV Taranu, E Pierri, J Ancerewicz, P Picavet, G Baker, C Haziza, F Lüdicke
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Peer-Reviewed Publication
July 29, 2017
Platform 1
Nicotine pharmacokinetic profiles of the Tobacco Heating System 2.2, cigarettes and nicotine gum in Japanese smokers
Patrick Brossard, R Weitkunat, V Poux, N Lama, C Haziza, P Picavet, G Baker, F Lüdicke
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Peer-Reviewed Publication
February 8, 2017
Platform 1
Effects of Switching to Tobacco Heating System 2.2 Menthol, Smoking Abstinence, or Continued Cigarette Smoking on Biomarkers of Exposure: A Randomized, Controlled, Open-Label, Multicenter Study in Sequential Confinement and Ambulatory Settings (Part 1)
F Lüdicke, P Picavet, G Baker, C Haziza, V Poux, N Lama, R Weitkunat
DOI : 10.1093/ntr/ntw287
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Peer-Reviewed Publication
February 8, 2017
Platform 1
Effects of Switching to Menthol THS2.2, Smoking Abstinence, or Continued Cigarette Smoking on Clinically Relevant Risk Markers: A Randomized, Controlled, Open-Label, Multicenter Study in Sequential Confinement and Ambulatory Settings (Part 2)
F Lüdicke, P Picavet, G Baker, C Haziza, V Poux, N Lama, R Weitkunat
DOI : 10.1093/ntr/ntx028
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Data
February 1, 2017
Biomarker of exposure level data set in smokers switching from conventional cigarettes to Tobacco Heating System 2.2, continuing smoking or abstaining from smoking for 5 days
C Haziza, G de La Bourdonnaye, D Skiada, J Ancerewicz, G Baker, P Picavet, F Lüdicke
DOI : 10.1016/j.dib.2016.11.047
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Peer-Reviewed Publication
January 4, 2017
Platform 1
Biomarker of exposure level data set in smokers switching from conventional cigarettes to Tobacco Heating System 2.2, continuing smoking or abstaining from smoking for 5 days
C Haziza, G de La Bourdonnaye, D Skiada, J Ancerewicz, G Baker, P Picavet, F Lüdicke
DOI : 10.1016/j.dib.2016.11.047
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Peer-Reviewed Publication
November 4, 2016
Platform 1
Evaluation of the Tobacco Heating System 2.2. Part 8: 5-Day randomized reduced exposure clinical study in Poland
C Haziza, G de La Bourdonnaye, D Skiada, J Ancerewicz, G Baker, P Picavet, F Lüdicke
Regulatory Toxicology and Pharmacology
DOI : 10.1016/j.yrtph.2016.11.003
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Presentation
October 8, 2016
Platform 1
THS2.2 – A Heat-not-Burn Product - Scientific Results to Date
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Peer-Reviewed Publication
October 5, 2016
Platform 1
Comparison of the Pharmacokinetics of Nicotine Following Single and Ad Libitum Use of a Tobacco Heating System or Combustible Cigarettes
DOI : 10.1093/ntr/ntv220
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Peer-Reviewed Publication
September 29, 2016
Platform 1
Assessment of the reduction in levels of exposure to harmful and potentially harmful constituents in Japanese subjects using a novel tobacco heating system compared with conventional cigarettes and smoking abstinence: A randomized controlled study in confinement
C Haziza, G de La Bourdonnaye, S Merlet, M Benzimra, J Ancerewicz, P Picavet, G Baker, F Lüdicke
Regulatory Toxicology and Pharmacology
DOI : 10.1016/j.yrtph.2016.09.014
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Poster
September 9, 2016
Platform 1
Reduced exposure to Harmful and Potentially Harmful Constituents after 90 days of use of tobacco heating system 2.2 in Japan: a comparison with continued cigarette use or smoking abstinence
F Lüdicke, C Haziza, N Lama, A Donelli, G Baker, J Ancerewicz, M Benzimra, M Franzon, M Endo*, P Picavet
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
July 1, 2016
Platform 1
Reduced Exposure to Harmful and Potentially Harmful Smoke Constituents with the Tobacco Heating System 2.1
DOI : 10.1093/ntr/ntw164
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Poster
June 17, 2016
Heated Tobacco Products
Comparing the Levels of Harmful Compounds in Smokers that either Continue to Smoke, Quit or Switch to THS2.2 Menthol (Japan)
C Haziza, N Lama, A Donelli, P Picavet, G Baker, J Ancerewicz, M Benzimra, M Franzon, M Endo*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
June 17, 2016
Heated Tobacco Products
Comparing The Levels Of Harmful Compounds In Smokers That Either Continue To Smoke, Quit Or Switch To THS2.2 Menthol (USA)
C Haziza, G de La Bourdonnaye, P Picavet, G Baker, D Skiada, S Merlet, M Franzon, F Farmer, W Lewis, F Lüdicke
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Infoposter
June 16, 2016
Platform 1
Comparing the levels of harmful compounds in smokers that either continue to smoke, quit or switch to THS2.2 menthol
C Haziza, N Lama, P Picavet, G Baker, J Ancerewicz, M Benzimra, M Franzon, M Endo*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
November 10, 2015
Reduced Exposure To Harmful And Potentially Harmful Constituents after 90 Days Of Use Of Tobacco Heating System 2.2 Menthol In Japan: A Comparison With Continued Cigarette Use Or Smoking Abstinence
C Haziza, N Lama, P Picavet, G Baker, J Ancerewicz, M Benzimra, M Franzon, M Endo*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
November 10, 2015
Heated Tobacco Products
Reduced exposure to harmful and potentially harmful constituents after 90 days of use of tobacco heating system 2.2 menthol in the U.S.: a comparison with continued cigarette use or smoking abstinence
C Haziza, G de La Bourdonnaye, P Picavet, G Baker, D Skiada, S Merlet, M Franzon, F Farmer, W Lewis, F Lüdicke
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Poster
March 23, 2015
Heated Tobacco Products
PK of Nicotine and Subjective Effects Following the Single Use of a Non-Menthol and Menthol Version of THS 2.2 in 2 Studies in Japan. A Comparison with Single Use of a Combustible Cigarette and Nicotine Gum
P Picavet, C Haziza, G Baker, N Lama, J Ancerewicz, M Benzimra, F Nobuoka*, M Sugimoto*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
March 23, 2015
Heated Tobacco Products
Reduced Exposure To Harmful And Potentially Harmful Constituents After Five Days of Use of Tobacco Heating System 2.2. A Comparison with Continued Combustible Cigarette Use or Smoking Abstinence [Poland]
C Haziza, G de La Bourdonnaye, P Picavet, G Baker, D Skiada, J Ancerewicz, K Jarus-Dziedzic*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Platform 1
Investigation on puffing topography parameters and product evaluation recorded during five days of use of the Tobacco Heating System 2.2: A comparison with continued combustible cigarette use
G de La Bourdonnaye, T Bachmann, C Haziza, P Picavet, G Baker, D Skiada, K Jarus-Dziedzic*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Heated Tobacco Products
Pharmacokinetics Of Nicotine And Subjective Effects Following The Single Use Of A Menthol Version Of Tobacco Heating System 2.2 In The US: A Comparison With Single Use Of A Combustible Cigarette And Nicotine Nasal Spray
C Haziza, G Baker, G de La Bourdonnaye, N Lama, J Ancerewicz, D Skiada, P Picavet, JL Borders*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Heated Tobacco Products
Reduced Exposure To Harmful And Potentially Harmful Constituents After Five Days Of Use Of tobacco Heating System 2.2: A Comparison With Continued Combustible Cigarette Use Or Smoking Abstinence [Japan]
C Haziza, G de La Bourdonnaye, G Baker, M Benzimra, J Ancerewicz, P Picavet, F Lüdicke
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Poster
February 28, 2015
Platform 1
Pharmacokinetics Of Nicotine And Subjective Effects Following The Single Use Of A Non-Menthol And Menthol Version Of Tobacco Heating System 2.2 In Two Studies In Japan: A Comparison With Single Use Of A Combustible Cigarette And Nicotine Gum
P Picavet, C Haziza, G Baker, N Lama, J Ancerewicz, M Benzimra, F Nobuoka*, M Sugimoto*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 4, 2014
Platform 1
Pharmacokinetics of nicotine following single use of a candidate modified risk tobacco product: the tobacco heating system 2.1
C Haziza, G Baker, J Ancerewicz, P Picavet, L Johnson, AJ Stewart*, F Lüdicke
* This author is not affiliated with PMI.
