Investigator Initiated Studies (IIS) Program

      As part of our vision of a smoke-free future, Philip Morris International (PMI) recognizes that independent research is critical to a thorough assessment of the risk-reduction potential of smoke-free products. This is why we support investigator initiated studies on our products, conducted by qualified third-party investigators. 

      How to apply

      We invite interested investigators to submit a study concept proposal to the IIS program. You can find here the guidelines and the terms and conditions of the program.

      Steps for application:

      1. Please fill out the short IIS concept proposal submission template.
      2. Submit your proposal in this template, and any questions about the submission process, via email to


      Topics of interest

      The scope of the IIS program includes aerosol chemistry, toxicology, systems biology, pre-clinical, and clinical studies. You can find the list of studies supported under the IIS program, both past and present. You can also find a list of IIS program publications.

      IIS Program

      Learn more about the IIS program

      You can check out the list of supported Investigator Initiated Studies and find the publications that have resulted from this program.

      Multiple transparent test tubes in laboratory.