4 October 2019
In 2012, the U.S. FDA published a list of harmful and potentially harmful constituents (HPHCs) found in tobacco products and smoke, known as the FDA 93 list as it comprises 93 compounds or classes of compounds. This list covers toxicants linked to diseases such as cancer and cardiovascular disease, among others. Below, we’ve listed the levels of those HPHCs (with the exception of nicotine) measured in the smoke of a standard reference cigarette (3R4F) and aerosols of two versions of our Tobacco Heating System (THS 2.2).
In all cases where a comparison could be made we found that HPHC levels in the THS were lower compared to 3R4F, with an average reduction of >90.5% for THS 2.2 Regular and >91.0% for THS 2.2 Smooth Menthol.
All analyses were conducted by Labstat International ULC (Kitchener, ON, Canada) according to their own methods and protocols. The standard Health Canada intense smoking regime was applied to both the 3R4F and the THS.