Methods and Protocols

      Analysis of volatiles and semi-volatiles in THS aerosol


      Published on
      Jun 7, 2018

      The aerosols are generated on a linear smoking machine and collected using Cambridge filter pad (CFP) followed by two micro impingers at 0 °C and -70 °C respectively, filled with 10 mL of methanol. The content of the CFP is then combined and extracted with the content of the impingers and delivered to the analytical laboratory. After filtration, the internal standards are added to the samples. The extracts are then analyzed by Gas Chromatography with Mass Spectrometry detection (GC-MS) using a column DB-WAXETR, 30 m x 0.25 mm ID x 0.5 μm (film thickness). Results are expressed as μg/item for the Tobacco Heating System (THS), referred to as Platform 1 (P1) in the method.