Methods and Protocols

    Analysis of volatiles and semi-volatiles in THS aerosol

    PMI

    Published on
    Jun 7, 2018
    Topic
    Summary

    The aerosols are generated on a linear smoking machine and collected using Cambridge filter pad (CFP) followed by two micro impingers at 0 °C and -70 °C respectively, filled with 10 mL of methanol. The content of the CFP is then combined and extracted with the content of the impingers and delivered to the analytical laboratory. After filtration, the internal standards are added to the samples. The extracts are then analyzed by Gas Chromatography with Mass Spectrometry detection (GC-MS) using a column DB-WAXETR, 30 m x 0.25 mm ID x 0.5 μm (film thickness). Results are expressed as μg/item for the Tobacco Heating System (THS), referred to as Platform 1 (P1) in the method.

    Related Publications

    Indoor Air Chemistry - An exploratory study on e-cigarette shows no negative impact on indoor air quality

    Aerosol Chemistry

    Indoor air chemistry - An exploratory study on e-cigarette shows no negative impact on indoor air quality

    Aerosol Chemistry

    Computer-Assisted Structure Identification (CASI) for high-throughput identification of small molecules using GC×GC-HRAM-TOFMS high-resolution accurate mass spectrometry

    Aerosol Chemistry

    Computer-Assisted Structure Identification (CASI) for high-throughput identification of small molecules using GC×GC-HRAM-TOFMS high-resolution accurate mass spectrometry

    Aerosol Chemistry

    Air quality assessment during indoor use of the Tobacco Heating System 2.2

    Aerosol Chemistry

    Air quality assessment during indoor use of the Tobacco Heating System THS 2.2

    Aerosol Chemistry

    PMIScience.com is operated by Philip Morris International for the purpose of publishing and disseminating scientific information about Philip Morris International’s efforts in support of its smoke-free product portfolio. This site is a global site for use by scientists, the public health and regulatory communities, and other stakeholders with an interest in tobacco policy. The purpose of this site is not advertising or marketing, nor is it directed at any specific market. It is not intended for use by consumers. New tobacco products sold in the United States are subject to FDA regulation; therefore the content of this site is not intended to make, and nor should it be construed as making, any product related claims in the United States without proper FDA authorization. ​
    ​
    Reduced Risk Products ("RRPs”) is the term we use to refer to products that present, are likely to present, or have the potential to present less risk of harm to smokers who switch to these products versus continuing smoking. PMI has a range of RRPs in various stages of development, scientific assessment and commercialization. All of our RRPs are smoke-free products that deliver nicotine with far lower quantities of harmful and potentially harmful constituents than found in cigarette smoke.