Methods and Protocols

      Analysis of volatiles and semi-volatiles in THS aerosol

      PMI

      Published on
      Jun 7, 2018
      Topic
      Summary

      The aerosols are generated on a linear smoking machine and collected using Cambridge filter pad (CFP) followed by two micro impingers at 0 °C and -70 °C respectively, filled with 10 mL of methanol. The content of the CFP is then combined and extracted with the content of the impingers and delivered to the analytical laboratory. After filtration, the internal standards are added to the samples. The extracts are then analyzed by Gas Chromatography with Mass Spectrometry detection (GC-MS) using a column DB-WAXETR, 30 m x 0.25 mm ID x 0.5 μm (film thickness). Results are expressed as μg/item for the Tobacco Heating System (THS), referred to as Platform 1 (P1) in the method.

      Related Publications

      Investigation of solid particles in the mainstream aerosol of the Tobacco Heating System THS2.2 and mainstream smoke of a 3R4F reference cigarette

      Aerosol Chemistry

      Application of secondary electrospray ionization coupled with high-resolution mass spectrometry in chemical characterization of thermally generated aerosols

      Aerosol Chemistry

      Comprehensive Chemical Characterization of the Aerosol Generated by a Heated Tobacco Product

      Aerosol Chemistry

      Comprehensive Chemical Characterization of the Aerosol Generated by Heated Tobacco Product

      Aerosol Chemistry

      Scientific substantiation of the absence of Environmental Tobacco Smoke (ETS) emission during use of the Electrically Heated Tobacco System (EHTS)

      Aerosol Chemistry

      What is combustion and why the absence of combustion is important in Heated Tobacco Products?

      Aerosol Chemistry

      PMIScience.com is operated by Philip Morris International for the purpose of publishing and disseminating scientific information about Philip Morris International’s efforts to develop and assess products that have the potential to reduce individual risk and population harm associated with tobacco use. This site is for use by scientists, the public health and regulatory communities, and other stakeholders with an interest in tobacco policy. The purpose of this site is not for advertising or marketing. It is not intended for use by consumers.

      Reduced Risk Products ("RRPs”) is the term we use to refer to products that present, are likely to present, or have the potential to present less risk of harm to smokers who switch to these products versus continuing smoking. PMI has a range of RRPs in various stages of development, scientific assessment and commercialization. Our RRPs are smoke-free products that produce an aerosol that contains far lower quantities of harmful and potentially harmful constituents than found in cigarette smoke.