Clinical Studies

    Nicotine Pharmacokinetics of THS Single Use of a Regular or a Menthol Stick Compared to CIG

    First posted
    Mar 29, 2023
    Identifier
    NCT05789420
    Publication Site URL
    Topic
    Official Title

    A Single-center, Randomized, Controlled, Open-label Study in Smoking Healthy Subjects to Investigate the Nicotine Pharmacokinetic Profiles Following Single Use of Tobacco Heating System (THS) With a Regular or a Menthol Stick, Compared to Smoking of a Single Combustible Cigarette (CIG)

    Brief Summary

    The purpose of this study is to describe the nicotine pharmacokinetic (PK) profile during and after single use of THS (Induction heating technology, with either a regular or menthol stick) compared to singular CIG smoking in healthy adult subjects. In addition, pharmacodynamic effects (subjective effects) will be evaluated to provide further insights on product acceptance and likelihood to use the THS again. Safety will be assessed throughout the study.

    Summary

    Recruitment: Completed

    Study Results: Results Available

    Enrollment (actual): 31

    Study Type: Interventional

    Other IDs: P1-PK-12

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