Methods and Protocols

      Procedure for generation and testing of mainstream Tobacco Heating System (THS or IQOS) aerosol using a linear smoking machine


      Published on
      Aug 17, 2016

      Cigarette smoke is produced when the tobacco in a cigarette burns at temperatures in excess of 600 °C. At such high temperatures, the tobacco is burned to ash and generates smoke that contains thousands of chemicals, including high levels of harmful and potentially harmful constituents (HPHCs), which are widely recognized to be the most likely causes of smoking-related diseases.

      The Tobacco Heating System (THS or IQOS, its commercial name), on the other hand, heats tobacco without burning it (combusting) to generate a nicotine-containing aerosol with significantly lower levels of HPHCs. HPHC levels can be measured by collecting the aerosol from IQOS, using a commercial linear smoking machine. This document provides a detailed description of how the device should be used in this context and step by step instructions for collecting the aerosol of IQOS using a  commercial linear smoking machine.