Peer-Reviewed Publications

    The ability of the FTC method to quantify nicotine as a function of ammonia in mainstream smoke

    Callicutt, C. H.; Cox, R. H.; Farthing, D.; Hsu, F. S.; Johnson, L.; Laffoon, S.; Lee, P.; Kinser, R. D.; Podraza, K. F.; Sanders, E. B.; Seeman, J. I.
    Published
    Mar 17, 2006
    DOI
    10.2478/cttr-2013-0818
    Link to publication
    Topic
    Summary

    Whether ammonia-forming ingredients added to tobacco and ammonia in smoke affect the ability of the Cambridge filter pad to trap nicotine in the federal trade commission (FTC) method was examined. Three commercial cigarettes, two industry reference cigarettes, and four specially designed test cigarettes were used in this study to represent cigarettes with different construction and mainstream (MS) smoke yield characteristics. One of the commercial cigarettes, a us 1998 Marlboro lights (R) king size cigarette, was used as a control cigarette for the four experimental test cigarettes. The test cigarettes differed from the control cigarette as follows: first, a reduction in ammonia-forming ingredients added to the reconstituted tobaccos; second, no ammonia-forming ingredients added to the reconstituted tobacco; third, no ingredients at all added to the reconstituted tobaccos; and fourth, no ingredients at all added to the entire tobacco blend. An XAD-4 tube was placed downstream of the standard Cambridge filter pad in the FTC method to trap the gas-vapor phase nicotine for subsequent analysis. The Cambridge filter pad used in the FTC method was determined to provide greater than 99% trapping efficiency for MS smoke nicotine from cigarettes with widely different soluble ammonia levels in filler and MS smoke ammonia yields.

    Related Publications

    Indoor Air Chemistry - An exploratory study on e-cigarette shows no negative impact on indoor air quality

    Aerosol Chemistry

    Indoor air chemistry - An exploratory study on e-cigarette shows no negative impact on indoor air quality

    Aerosol Chemistry

    Computer-Assisted Structure Identification (CASI) for high-throughput identification of small molecules using GC×GC-HRAM-TOFMS high-resolution accurate mass spectrometry

    Aerosol Chemistry

    Computer-Assisted Structure Identification (CASI) for high-throughput identification of small molecules using GC×GC-HRAM-TOFMS high-resolution accurate mass spectrometry

    Aerosol Chemistry

    Air quality assessment during indoor use of the Tobacco Heating System 2.2

    Aerosol Chemistry

    Air quality assessment during indoor use of the Tobacco Heating System THS 2.2

    Aerosol Chemistry

    PMIScience.com is operated by Philip Morris International for the purpose of publishing and disseminating scientific information about Philip Morris International’s efforts in support of its smoke-free product portfolio. This site is a global site for use by scientists, the public health and regulatory communities, and other stakeholders with an interest in tobacco policy. The purpose of this site is not advertising or marketing, nor is it directed at any specific market. It is not intended for use by consumers. New tobacco products sold in the United States are subject to FDA regulation; therefore the content of this site is not intended to make, and nor should it be construed as making, any product related claims in the United States without proper FDA authorization. ​
    ​
    Reduced Risk Products ("RRPs”) is the term we use to refer to products that present, are likely to present, or have the potential to present less risk of harm to smokers who switch to these products versus continuing smoking. PMI has a range of RRPs in various stages of development, scientific assessment and commercialization. All of our RRPs are smoke-free products that deliver nicotine with far lower quantities of harmful and potentially harmful constituents than found in cigarette smoke.