Peer-Reviewed Publications

    A network-based approach to quantifying the impact of biologically active substances

    Hoeng, J.; Deehan, R.; Pratt, D.; Martin, F.; Sewer, A.; Thomson, T. M.; Drubin, D. A.; Waters, C. A.; de Graaf, D.; Peitsch, M. C.
    Published
    Dec 1, 2011
    DOI
    10.1016/j.drudis.2011.11.008
    PMID
    22155224
    Link to publication
    Topic
    Summary

    Society increasingly demands close scrutiny of the potential health risks of long-term exposure to biologically active substances, such as therapeutic drugs or environmental toxins. Such risks are typically assessed a posteriori through clinical epidemiology studies. However, disease might take decades to manifest, at a point where changes in therapeutic regime, life style or exposure would not prevent disease onset.

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