Clinical Studies

Prefatory Study to Explore Changes in Nasal Mucociliary Clearance and to Standardize Nasal Scraping Procedure

First posted
Mar 22, 2017
Identifier
NCT03086707
Publication Site URL
Topic
Official Title

A 2-arm, Open Label, Prefatory Study to Explore Changes in Nasal Mucociliary Clearance Between Smokers and Never Smokers and to Standardize Nasal Scraping Procedure

Brief Summary

This study intends to evaluate the nasal mucociliary clearance (NMC) by determining the value obtained for saccharin transit time (STT) test over the course of 12 hours following a single cigarette use in smokers, to compare it relative to never smokers, and to examine the relationship between plasma nicotine levels and STT value in smokers and never smokers. Safety will also be monitored during the study.The planned maximum study duration for a single study participant from Screening through completion of study will be 33 days.

Summary

Recruitment: Completed

Study Results: Available

Enrollment: 14

Study Type: Interventional

Other IDs: P1-CMS-01-US

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