Peer-Reviewed Publications

    Rapid and sensitive method for the determination of propylene oxide in cigarette mainstream smoke by gas chromatography-mass spectrometry

    Diekmann, J.; Douda, M.; Rustemeier, K.
    Published
    Jan 1, 2006
    DOI
    10.1093/chromsci/44.1.32
    PMID
    16599409
    Link to publication
    Topic
    Summary

    A rapid method using gas chromatography-mass spectrometry for the analysis of propylene oxide in cigarette mainstream smoke is reported. Validation data show the method, which requires a minimum of sample preparation, to be selective, sensitive, reliable, and robust. Propylene oxide is found in the University of Kentucky Reference Cigarettes 1R4F and 2R4F at concentrations of 0.93 and 0.65 µg/cigarette, respectively, with a quantitation limit of 0.135 µg/cigarette.

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