OPEN SCIENCE, FEBRUARY 2022

      Getting it right: ENDS and HTPs: Challenges and pitfalls in aerosol analysis 

      In this Open Science event, we explained how emissions from smoke-free products, such as Electronic Nicotine Delivery Systems (ENDS) and heated tobacco products (HTPs), were measured, discussed the importance of this research, and reviewed findings from independent studies on the topic.

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      Scientific methods for analyzing harmful chemicals in aerosols

      Nicotine, though addictive and not risk free, is not the primary cause of smoking-related diseases. Therefore, the innovation of products that have a nicotine-containing aerosol, without tobacco combustion, can provide adult smokers with a better alternative if they intend to continue smoking. 

      With every new product that is developed, we need to accurately measure the levels of harmful or potentially harmful chemicals. In addition, the characterization of the aerosol needs to be carried out to ensure that not only levels of these chemicals are reduced, compared with cigarette smoke, but also whether no new harmful compounds are formed. 

      This is why the methods that we at Philip Morris International (PMI), and others, use to analyze these chemicals are so important, and this is the topic that was addressed during Open Science in Brief February 2022. 

      Three of our leading scientists Moira Gilchrist, VP Strategic & Scientific Communications, Maurice Smith, Senior Scientific Advisor, and Catherine Goujon-Ginglinger, Head of Chemistry Research, discussed the analysis of both targeted and untargeted screening of toxicants in the aerosols of smoke-free products and other alternatives. They also discussed external publications that have touched on this issue.

      Read these publications for more details:

      Event details

      Open Science in Brief

      This Open Science event was held in February 2022.

       

      The 30-minute session was hosted on our Open Science platform, and was simultaneously broadcasted on PMIScience LinkedIn®.

      Watch the replay
      Open Science Speakers

      E-cigarettes and heated tobacco products: Analyzing aerosol composition

      In this Open Science Event, two of our leading scientists provide their perspectives on the methods and approaches that PMI uses to address the difficulties inherent to aerosol analysis. Together, they discuss why having a quality management system is so important for their research and go into depth on both targeted and untargeted analysis of toxicants in the aerosols of smoke-free products and other alternatives. They also comment on the strengths and weaknesses of independent studies that have been conducted in this area. 

      Other points mentioned during the live Q&A session in the second half of the video involve the necessity for a reference e-cigarette and PMI’s engagement with the scientific community. Discover more about aerosol analysis by watching the video. 

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      PMIScience.com is operated by Philip Morris International for the purpose of publishing and disseminating scientific information about Philip Morris International’s efforts in support of its smoke-free product portfolio. This site is a global site for use by scientists, the public health and regulatory communities, and other stakeholders with an interest in tobacco policy. The purpose of this site is not advertising or marketing, nor is it directed at any specific market. It is not intended for use by consumers. New tobacco products sold in the United States are subject to FDA regulation; therefore the content of this site is not intended to make, and nor should it be construed as making, any product related claims in the United States without proper FDA authorization. ​
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      Reduced Risk Products ("RRPs”) is the term we use to refer to products that present, are likely to present, or have the potential to present less risk of harm to smokers who switch to these products versus continuing smoking. PMI has a range of RRPs in various stages of development, scientific assessment and commercialization. All of our RRPs are smoke-free products that deliver nicotine with far lower quantities of harmful and potentially harmful constituents than found in cigarette smoke.