-
Clinical Study
January 13, 2017
Platform 1
An Observational Cohort Study in Japan to Assess the Patterns of Product Use and Changes in Health Outcomes Associated With the Use of HeatSticks With the Tobacco Heating System
PMI
-
Clinical Study
November 10, 2010
A European, Multi-centre Study to Determine the Exposure of Adult Smokers and Non-smokers to Cigarette Smoke Constituents
PMI
-
Clinical Study
January 31, 2013
Platform 1
A Single-center, Open-label, Randomized, Controlled, Crossover Study to Explore the Nicotine Pharmacokinetic Profile and Safety of Tobacco Heating System (THS) 2.1 Compared to Conventional Cigarettes Following Single and ad Libitum Use in Smoking, But Otherwise Healthy Subjects.
PMI
-
Clinical Study
January 31, 2013
Platform 1
A Single-center, Open-label, Randomized, Controlled, 2-arm Parallel Group Study to Evaluate the Exposure to Selected Smoke Constituents in Smoking, But Otherwise Healthy Subjects Switching From Conventional Cigarettes to the Tobacco Heating System (THS) 2.1
PMI
-
Clinical Study
December 7, 2017
Platform 1
A 6-month Randomized, Controlled, Open-label, 2-arm Parallel Group, Multicenter Study to Evaluate the Effect of Switching From Cigarette Smoking to the Use of Platform 1 in Smokers With Generalized Chronic Periodontitis on the Response to Mechanical Periodontal Treatment and Oral Health Status.
PMI
-
Clinical Study
December 20, 2017
Platform 4
A Single-center, Open-label, Concentration-ranging Study to Investigate the Nicotine Pharmacokinetic Profiles and Pharmacodynamic Effects of the P4M3 Variants
PMI
-
Clinical Study
May 16, 2018
Cross Sectional Survey on the Use of Tobacco Products in the General Population and in Users of Platform 1 in Italy (2018-2020)
PMI
-
Clinical Study
May 16, 2018
Cross Sectional Survey on the Use of Tobacco Products in the General Population and in Users of Platform 1 in London (2018-2020)
PMI
-
Clinical Study
June 11, 2018
Platform 1
Assessment of passive environmental aerosol exposure through the Tobacco Heating System (THS) in a restaurant setting where THS use, but not cigarette smoking, is allowed
PMI
-
Peer-Reviewed Publication
June 30, 2018
Characterization and modeling of aerosol deposition in Vitrocell® exposure systems - exposure well chamber deposition efficiency
F Lucci, ND Castro*, AA Rostami*, M Oldham*, J Hoeng, YB Pithawalla*, A Kuczaj
* This author is not affiliated with PMI.Volume 123, September 2018, Pages 141-160
DOI : 10.1016/j.jaerosci.2018.06.015
-
Peer-Reviewed Publication
July 9, 2018
Delivery efficiencies of constituents of combustion-derived aerosols across the air-liquid interface during in vitro exposures
S Steiner, P Diana, E Dossin, P Guy, G Vuillaume, A Kondylis, S Majeed, S Frentzel, J Hoeng
DOI : 10.1016/j.tiv.2018.06.024
-
Peer-Reviewed Publication
July 2, 2018
Platform 1
Role of testing standards in smoke-free product assessments
M Belushkin, M Esposito, G Jaccard, C Jeannet, A Korneliou, D Tafin Djoko
Regulatory Toxicology and Pharmacology
Volume 98, October 2018, Pages 1-8
DOI : 10.1016/j.yrtph.2018.06.021
-
Peer-Reviewed Publication
June 12, 2011
Modeling Early Initiation Processes in Smoking-Induced Lung Adenocarcinomas
G Vuillaume, T Mueller, M Talikka, Y Cheng, G Diserens, M Peitsch, J Hoeng, F Tobin*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
January 1, 2017
Menthol Cigarettes, Time to First Cigarette, and Smoking Cessation
EB Sanders, R Weitkunat, R Dempsey
-
Peer-Reviewed Publication
March 1, 2017
The Adverse Outcome Pathway for Oxidative Stress-Mediated EGFR Activation Leading to Decreased Lung Function
K Luettich, M Talikka, FJ Lowe*, LE Haswell, J Park*, M Gaca*, J Hoeng
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
March 1, 2017
Development of an adverse outcome pathway for the onset of hypertension by oxidative stress-mediated perturbation of endothelial nitric oxide bioavailability
FJ Lowe*, K Luettich, M Talikka, V Hoang*, LE Haswell, J Hoeng, M Gaca*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
March 31, 2017
Systems toxicology: Real World Applications and Opportunities
T Hartung*, RE FitzGerald*, P Jennings*, Gary R. Mirams*, M Peitsch, A Rostami-Hodjegan*, I Shah*, MF Wilks*, SJ Sturla*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
September 5, 2017
Supporting evidence-based analysis for modified risk tobacco products through a toxicology data-sharing infrastructure.
S Boue, T Exner*, D Ghosh, V Belcastro, J Dokler*, D Page, A Boda, F Bonjour, B Hardy*, P Vanscheeuwijck, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
March 19, 2016
Evaluation of oscillation-free fluid-porous interface treatments for segregated finite volume flow solvers
M Stanic*, M Nordlund, EM Frederix*, A Kuczaj, BJ Geurts*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
June 30, 2018
Advancing Risk Assessment through the Application of Systems Toxicology.
JM Sauer*, A Kleensang*, M Peitsch, AW Hayes
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
January 22, 2016
Heterocyclic aromatic amines and their contribution to the bacterial mutagenicity of the particulate phase of cigarette smoke.
E Roemer, T Meisgen, J Diekmann, LL Conroy, R Stabbert
-
Peer-Reviewed Publication
May 15, 2016
Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing.
U Marx*, TB Andersson *, A Bahinski*, M Beilmann*, S Beken*, FR Cassee*, M Cirit*, M Daneshian *, S Fitzpatrick*, O Frey *, C Gaertner*, C Giese *, L Griffith *, T Hartung*, MB Heringa*, J Hoeng, WH de Jong *, H Kojima*, J Kuehnl*, M Leist*, A Luch *, I Maschmeyer*, D Sakharov*, AJAM Sips*, T Steger-Hartmann*, DA Tagle*, A Tonevitsky *, T Tralau*, S Tsyb*, A van de Stolpe *, R Vandebriel*, P Vulto*, J Wang*, J Wiest*, M Rodenburg*, A Roth*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
August 20, 2016
Training and evaluation corpora for the extraction of causal relationships encoded in biological expression language (BEL)
J Fluck*, S Madan*, S Ansari, AT Kodamullil*, R Karki*, M Rastegar-Mojarad*, NL Catlett*, WS Hayes, J Szostak, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
December 31, 2016
Improved knowledge acquisition and creation of structured knowledge for systems toxicology.
S Ansari, J Szostak, M Talikka, J Fluck*, J Hoeng
* This author is not affiliated with PMI.International Journal On Advances in Life Sciences
Int J Adv Life Sci 8: 309-319.
-
Peer-Reviewed Publication
January 5, 2016
Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice.
S Ansari, K Baumer, S Boue, S Dijon, R Dulize, K Ekroos*, A Elamin, C Foong, E Guedj, J Hoeng, NV Ivanov, AS Krishnan *, P Leroy, F Martin, C Merg, M Peck, M Peitsch, B Phillips, W Schlage, T Schneider, M Talikka, B Titz, P Vanscheeuwijck, E Veljkovic, T Vihervaara*, G Vuillaume, CQ Woon
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
June 9, 2018
Platform 1
Thermal decomposition behavior of the tobacco material used in a heated tobacco product
-
Poster
June 8, 2018
Platform 1
Non-targeted screening using GC×GC-TOFMS for in-depth chemical characterization of aerosol from a heat-not-burn tobacco product
M Almstetter, A Knorr, M Rhouma, E Martin, A Castellon, P Pospisil, M Bentley
-
Poster
June 8, 2018
Platform 1
Computer-Assisted Structure Identification (CASI) for high-throughput identification of small molecules using GC×GC-HRAM-TOFMS high-resolution accurate mass spectrometry
A Knorr, E Martin, M Almstetter, A Castellon, P Pospisil, M Bentley
-
Poster
June 8, 2018
Increasing confidence for compound identification by fragmentation database and in silico fragmentation comparison with LC-HRAM-MS-based non-targeted screening of complex matrices
C Buchholz, D Arndt, C Wachsmuth, M Bentley
-
Peer-Reviewed Publication
June 20, 2018
Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity
AJ Clippinger*, D Allen*, HP Behrsing *, KA BéruBé*, MB Bolger*, W Casey*, M DeLorme*, M Gaca*, SC Gehen*, K Glover*, P Hayden*, P Hinderliter*, JA Hotchkiss*, A Iskandar, B Keyser*, K Luettich, L Ma-Hock*, A Maione*, P Makena*, J Melbourne*, L Milchak*, SP Ng*, A Paini*, K Page*, G Patlewicz*, P Prieto*, H Raabe*, EN Reinke*, C Roper*, J Rose*, M Sharma*, W Spoo*, PS Thorne*, DM Wilson*, AM Jarabek*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
June 9, 2018
Modeling the impact of changes in tobacco use on individual disease risks
S Djurdjevic, Z Sponsiello Wang, PN Lee*, JS Fry*, R Weitkunat, F Lüdicke, G Baker
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
June 22, 2018
Platform 4
Physicochemical studies of direct interactions between lung surfactant and components of electronic cigarettes liquid mixtures
TR Sosnowski*, K Jabłczyńska*, M Odziomek*, W Schlage, A Kuczaj
* This author is not affiliated with PMI.DOI : 10.1080/08958378.2018.1478916
-
Peer-Reviewed Publication
June 16, 2018
Platform 1
Investigation and comparison of the transfer of TSNA from tobacco to cigarette mainstream smoke and to the aerosol of a heated tobacco product, THS2.2
G Jaccard, A Kondylis, I Gunduz, J Pijnenburg, M Belushkin
-
Peer-Reviewed Publication
January 18, 2015
Synergy, suppression and immorality: forward differences of the entropy function.
J Whittaker*, F Martin, Y Xiang
* This author is not affiliated with PMI.1501.04368
-
Peer-Reviewed Publication
June 17, 2015
Construction of biological networks from unstructured information based on a semi-automated curation workflow.
J Szostak, S Ansari, S Madan*, J Fluck*, M Talikka, A Iskandar, H De Leon, M Hofmann-Apitius*, M Peitsch, J Hoeng
* This author is not affiliated with PMI.DOI : 10.1093/database/bav057
-
Peer-Reviewed Publication
March 23, 2015
Systems Toxicology: The Future of Risk Assessment.
JM Sauer*, T Hartung*, M Leist*, TB Knudsen*, J Hoeng, AW Hayes
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
May 1, 2015
An Improved GC-MS Method for Cigarette Smoke Characterization Using a Novel Cold Trap, Dual Column, and Cryofocusing System
M Rotach, E G R Rouget, J R Crudo
Volume 28, Issue 5, pg 258–264
-
Peer-Reviewed Publication
May 19, 2015
Automation of the in vitro micronucleus and chromosome aberration assay for the assessment of the genotoxicity of the particulate and gas–vapor phase of cigarette smoke.
E Roemer, V Zenzen, LL Conroy, K Luedemann, R Dempsey, C Schunck*, E TrellesSticken*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
July 2, 2015
Systems biology reveals cigarette smoke-induced concentration-dependent direct and indirect mechanisms that promote monocyte-endothelial cell adhesion.
-
Peer-Reviewed Publication
November 3, 2014
Differences in cadmium transfer from tobacco to cigarette smoke, compared to arsenic or lead
JJ Piadé, G Jaccard, C Dolka, M Belushkin, S Wajrock
-
Peer-Reviewed Publication
May 26, 2015
Median estimation of chemical constituents for sampling on two occasions under a log-normal model.
A Kondylis
-
Peer-Reviewed Publication
August 13, 2015
Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells.
U Kogel, I Gonzalez-Suarez, Y Xiang, E Dossin, P Guy, C Mathis, D Marescotti, D Goedertier, F Martin, M Peitsch, J Hoeng
-
Peer-Reviewed Publication
February 15, 2015
Where are we at regarding species translation? A review of the sbv IMPROVER challenge.
J Hoeng, M Peitsch, P Meyer*, I Jurisica
* This author is not affiliated with PMI.Volume 31, Issue 4, Pages 451–452,
-
Peer-Reviewed Publication
April 30, 2015
Extension of the compressible PISO algorithm to single-species aerosol formation and transport
EM Frederix*, M Stanic*, A Kuczaj, M Nordlund, BJ Geurts*
* This author is not affiliated with PMI.International Journal of Multiphase Flow
Volume 74, September 2015, Pages 184-194
DOI : 10.1016/j.ijmultiphaseflow.2015.04.015
-
Peer-Reviewed Publication
June 25, 2015
Considerations for comparative tobacco product assessments based on smoke constituent yields
M Belushkin, G Jaccard, A Kondylis
Regulatory Toxicology and Pharmacology
Volume 73, Issue 1, October 2015, Pages 105-113
DOI : 10.1016/j.yrtph.2015.06.017
-
Peer-Reviewed Publication
February 7, 2014
Direct action and modulating effect of (+)- and (-)-nicotine on ion channels expressed in trigeminal sensory neurons
BSP Schreiner*, R Lehmann*, U Thiel*, PM Ziemba*, LR Beltrán*, MA Sherkheli*, P Jeanbourquin, A Hugi, M Werner*, G Gisselmann*, H Hatt*
* This author is not affiliated with PMI.European Journal of Pharmacology
Volume 728, 5 April 2014, Pages 48-58
DOI : 10.1016/j.ejphar.2014.01.060
-
Peer-Reviewed Publication
June 13, 2014
A decade of Systems Biology: where are we and where are we going to?
M Peitsch, D de Graaf*
* This author is not affiliated with PMI.DOI : 10.1016/j.drudis.2013.06.002
-
Peer-Reviewed Publication
January 1, 2013
A modular cell-type focused inflammatory process network model for non-diseased pulmonary tissue.
JW Westra*, W Schlage, A Hengstermann*, S Gebel*, C Mathis, TM Thomson, B Wong*, V Hoang*, E Veljkovic, M Peck, RB Lichtner, D Weisensee, M Talikka, R Deehan*, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
November 11, 2013
Computer-assisted structure identification (CASI)--an automated platform for high-throughput identification of small molecules by two-dimensional gas chromatography coupled to mass spectrometry.
A Knorr, A Monge, M Stueber, A Stratmann, D Arndt, E Martin, P Pospisil
-
Peer-Reviewed Publication
December 5, 2013
Assessing smoking behaviour and tobacco smoke exposure: definitions and methods
E Gregg*, T Bachmann, R Bito*, X Cahours*, M McEwan*, P Nelson*, K Prasad*, G Scherer*, M Stiles*
* This author is not affiliated with PMI.Beiträge zur Tabakforschung International
Volume 25, No. 8
-
Peer-Reviewed Publication
August 15, 2013
Menthol addition to cigarettes using breakable capsules in the filter. Impact on the mainstream smoke yields of the Health Canada list constituents.
C Dolka, JJ Piadé, M Belushkin, G Jaccard
Chemical Research in Toxicology
DOI : 10.1021/tx400146x
-
Peer-Reviewed Publication
January 12, 2012
Does the use of ingredients added to tobacco increase cigarette addictiveness?: a detailed analysis.
EB Sanders, R Weitkunat, A Utan, R Dempsey
DOI : 10.3109/08958378.2012.663006
-
Peer-Reviewed Publication
February 6, 2012
Headspace Volumetric Karl Fischer Titration for the Determination of Water Content in Finished Tobacco Products
N Aydin, F Chardonnens, M Rotach
-
Peer-Reviewed Publication
February 14, 2011
Limitations of cigarette machine smoking regimens.
E Roemer, RA Carchman*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
July 10, 2011
Comparison of exposure to selected cigarette smoke constituents in adult smokers and nonsmokers in a European, multicenter, observational study.
D Lindner, S Smith*, C Martin Leroy, A R Tricker
* This author is not affiliated with PMI.Cancer Epidemiology, Biomarkers & Prevention
DOI : 10.1158/1055-9965.EPI-10-1186
-
Peer-Reviewed Publication
December 13, 2010
Cigarette smoke enhances abdominal aortic aneurysm formation in angiotensin II-treated apolipoprotein E-deficient mice.
K Stolle, A Berges, M Lietz, S Lebrun, T Wallerath
-
Peer-Reviewed Publication
December 30, 2014
The Addition of Cocoa, Glycerol, and Saccharose to the Tobacco of Cigarettes: Implications for Smoke Chemistry, In Vitro Cytotoxicity, Mutagenicity and Further Endpoints
E Roemer, S Wittke, E TrellesSticken*, JJ Piade*, T Bonk, MK Schorp*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
June 10, 2009
Biotransformation of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in Lung Tissue from Mouse, Rat, Hamster, and Man
E Richter*, J Engl*, S Friesenegger*, A R Tricker
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
December 30, 2014
A Modelling Approach to Develop Machine Smoking Protocols Reflecting Human Puffing Behaviour for Conventional Cigarettes
HJ Urban, W Gomm, MK Schorp*
* This author is not affiliated with PMI.DOI : 10.2478/cttr-2013-0844
-
Peer-Reviewed Publication
January 10, 2009
Systematic review of the relation between smokeless tobacco and cancer of the pancreas in Europe and North America
Z Sponsiello Wang, R Weitkunat, PN Lee*
* This author is not affiliated with PMI. -
Infoposter
June 15, 2018
Platform 1
Product experience and risk perceptions in Platform 1 users: a cross-sectional survey in Japan
P Langer, Z Sponsiello Wang, L Prieto, M Dobrynina, D Skiada, N Camille, R Weitkunat, F Lüdicke
-
Infoposter
June 15, 2018
Potential Predictors of Intended Use of a Novel Heat-Not-Burn Tobacco Product
F Beacher, PP Magnani, A Ramazzotti, S Colman*, F Lüdicke, R Weitkunat, G Kallischnigg, B Zwisele*
* This author is not affiliated with PMI. -
Infoposter
June 15, 2018
A Multi-Center, Multi-Regional, Study on Biological and Functional Changes in Healthy Adult Smokers during One Year of Continuous Smoking Abstinence
C Tran, Loyse Felber Medlin , N Lama, BV Taranu, E Pierri, J Ancerewicz, P Picavet, G Baker, C Haziza, F Lüdicke
-
Infoposter
June 15, 2018
Modeling the Population Health Impact of introducing a Reduced Risk Product into the Japan market
S Djurdjevic, G Baker, T Iida, E Konishi, F Lüdicke
-
Infoposter
June 15, 2018
Evaluation of biological and functional changes in healthy smokers after switching from cigarettes to Tobacco Heating System (THS) 2.2 for 6 months
S Ansari, N Lama, N Blanc, D Skiada, J Ancerewicz, P Picavet, G Baker, C Haziza, F Lüdicke
-
Infoposter
June 15, 2018
Assessing consumer responses to reduced risk products: experience at Philip Morris International in developing fit-for-purpose self-report instruments
C Chrea, E Spies, E Afolalu, N Mainy, S Gallot, P Binggeli, E Clerc, R Weitkunat, T Salzberger, S Cano, C Acquadro*, B Arnould*, V Brunel*, J Lambert*, C Marcuccilli*, L Abetz-Webb*, Jed E Rose PhD*, K Fagerström*
* This author is not affiliated with PMI. -
Presentation
June 15, 2018
Platform 1
Changes in Biological and Functional Markers after Six Months, in Three Populations: THS 2.2 (IQOS) Users, Continued Smokers, and Smoking Abstinence
C Haziza
-
Poster
June 11, 2018
Platform 1
Changes in Clinical Risk Endpoints Linked to Cardiovascular and Other Smoking-Related Diseases after Switching from Cigarettes to the Tobacco Heating System (THS) 2.2 for Six Months
C Haziza, S Ansari, N Lama, M Bosilkovska, N Blanc, D Skiada, J Ancerewicz, P Picavet, G Baker, F Lüdicke
-
Poster
June 11, 2018
Platform 1
Cardiovascular Effects Observed When Using the Tobacco Heating System (THS) 2.2 Compared with Continued Smoking
G Baker, C Haziza, J Hoeng, NV Ivanov, F Lüdicke, S Maeder, M Peitsch, B Phillips, P Picavet, C Poussin, P Vanscheeuwijck
-
Methods and Protocols
June 7, 2018
Platform 1
Determination of water, nicotine, triacetin in Platform 1 aerosol
PMI
-
Methods and Protocols
June 7, 2018
Platform 1
Analysis of volatiles and semi-volatiles in Platform 1 Aerosol
PMI
-
Peer-Reviewed Publication
March 7, 2018
Physiological and biological characterization of smokers with and without COPD.
N Chaudhary, K Luettich, M Peck, E Pierri, Loyse Felber Medlin , G Vuillaume, P Leroy, J Hoeng, M Peitsch
-
Book Chapter
May 23, 2018
Animal Inhalation Models to Investigate Modulation of Inflammatory Bowel Diseases
Experimental Animal Models of Human Diseases: An Effective Therapeutic Strategy
DOI : 10.5772/intechopen.69569
-
Poster
May 25, 2018
Enabling Systems Toxicology Assessment Studies with State-of-the-Art Biospecimen Data Management Systems
E Dargaud, S Ansari
-
Peer-Reviewed Publication
May 10, 2018
SolCyc: a database hub at the Sol Genomics Network (SGN) for the manual curation of metabolic networks in Solanum and Nicotiana specific databases
H Foerster*, A Bombarely*, JND Battey, N Sierro, NV Ivanov, LA Mueller*
* This author is not affiliated with PMI. -
Presentation
April 27, 2018
Platform 1
Clinical assessment of products aiming at reducing the risk of use compared with continued cigarette smoking
-
Poster
May 9, 2018
Human Research Investigation on the Effects of Cigarette Smoking, E-Cigarette Vaping, and Smoking Cessation on Vascular Cell Biology
C Poussin, J Hoeng, S Ansari, E Guedj, TM Curran*, LA Baglia*, RA Berg*, N Blumberg*, SL Spinelli*, Loyse Felber Medlin , NV Ivanov, P Picavet, M Peitsch
* This author is not affiliated with PMI. -
Poster
May 9, 2018
Platform 1
Systems Toxicological Assessment of two Modified Risk Tobacco Products on Cardiovascular and Respiratory Effects in ApoE-/-mice - a six-month inhalation study
B Phillips, J Szostak, E Guedj, E T Wong, M Talikka, S Lebrun, B Titz, F Martin, G Vuillaume, P Leroy, A Buettner*, NV Ivanov, P Vanscheeuwijck, M Peitsch, J Hoeng
* This author is not affiliated with PMI. -
Poster
May 5, 2018
Establishing the baseline effects of non-flavoured e-liquids and flavour compounds in the in vitro micronucleus assay
D Smart, P Vanscheeuwijck, D McHugh, E Nallet, FR Helbling
-
Poster
May 5, 2018
Mode-of-action analysis of a positive in vitro micronucleus finding in CHO-WBL cells
D McHugh, P Vanscheeuwijck, FR Helbling, D Smart
-
Presentation
May 5, 2018
Nicotine-Containing E-Vapor Products
Mode-of-action analysis of genotoxicity detected by the in vitro micronucleus assay: two industry case studies
D Smart
-
Presentation
May 21, 2018
Platform 1
Molecular biomarkers elucidate the role of inflammation and oxidative stress in smoking-related diseases
-
Peer-Reviewed Publication
April 19, 2018
Influence of smoking and smoking cessation on levels of urinary 11-dehydro thromboxane B2
A van der Plas, S Pouly, G de La Bourdonnaye, W Teck Ng, G Baker, F Lüdicke
DOI : 10.1016/j.toxrep.2018.04.005
-
Peer-Reviewed Publication
May 7, 2018
Next-generation tobacco and nicotine products: Substantiating harm reduction and supporting tobacco regulatory science
M Peitsch, R Polosa*, C Proctor*, T Hassler*, M Gaca*, E Hill*, J Hoeng, AW Hayes
* This author is not affiliated with PMI. -
Presentation
April 11, 2018
A review of analytical approaches to assess transitions in patterns of tobacco product use in the population
E Afolalu
-
Peer-Reviewed Publication
May 16, 2018
Platform 1
Modeling the Population Health Impact of Introducing a Modified Risk Tobacco Product into the U.S. Market
S Djurdjevic, PN Lee*, R Weitkunat, Z Sponsiello Wang, F Lüdicke, G Baker
* This author is not affiliated with PMI.DOI : 10.3390/healthcare6020047
-
Report
May 9, 2016
Appendix 2: Independent Expert Risk Benefit Assessment
R Bass*
* This author is not affiliated with PMI. -
Report
May 27, 2016
Appendix 1: Expert Report of Prof. Dr. Valerio Cozzani
V Cozzani*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
April 11, 2018
Platform 2
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology
B Phillips, W Schlage, B Titz, U Kogel, D Sciuscio, F Martin, P Leroy, G Vuillaume, AS Krishnan *, PN Lee*, E Veljkovic, A Elamin, C Merg, NV Ivanov, M Peitsch, J Hoeng, P Vanscheeuwijck
* This author is not affiliated with PMI.DOI : 10.1016/j.fct.2018.04.015
-
Peer-Reviewed Publication
December 14, 2017
Platform 1
Pre-market studies from five countries in Asia and Europe to measure the adoption of the tobacco heating system (THS) in smokers
S Roulet, N Mainy, C Chrea, PP Magnani, R Weitkunat, G Kallischnigg, A Ramazzotti
-
Peer-Reviewed Publication
December 15, 2017
Perceived risks associated with the use of tobacco and nicotine-containing products: Findings from qualitative research
T Salzberger, C Chrea, S Cano, M Martin, M Atkison*, G Emilien, N Mainy, A Ramazzotti, R Weitkunat, F Lüdicke
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
July 10, 2017
Nicotine-Containing E-Vapor Products
In vitro exposure systems and dosimetry assessment tools for inhaled tobacco products: Workshop proceedings, conclusions and paths forward for in vitro model use.
HP Behrsing *, H Raabe*, E Hill*, R Devlin*, S Fitzpatrick*, R Tice*, K Pinkerton*, G Oberdörster*, C Wright*, R Wieczorek*, M Aufderheide*, S Steiner, T Krebs*, B Asgharian*, R Corley*, M Oldham*, J Adamson*, X Li*, I Rahman*, S Grego*, PH Chu*, S McCullough*, R Curren*
* This author is not affiliated with PMI.45(3): 117-158.
-
Peer-Reviewed Publication
October 18, 2017
Simulation of size-dependent aerosol deposition in a realistic model of the upper human airways
EM Frederix*, A Kuczaj, M Nordlund, M Belka*, F Lizal*, J Jedelsky*, J Elcner*, M Jicha*, BJ Geurts*
* This author is not affiliated with PMI.DOI : 10.1016/j.jaerosci.2017.10.007
-
Peer-Reviewed Publication
March 13, 2018
Platform 2
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment
B Titz, U Kogel, F Martin, W Schlage, Y Xiang, C Nury, S Dijon, K Baumer, D Peric, D Bornand, R Dulize, B Phillips, P Leroy, G Vuillaume, S Lebrun, A Elamin, E Guedj, K Trivedi, NV Ivanov, P Vanscheeuwijck, M Peitsch, J Hoeng
DOI : 10.1016/j.fct.2018.02.058
-
Poster
March 16, 2018
Four-Week Continuous Nicotine Treatment of Immortalized Bronchial Epithelial Cells Does Not Contribute to Tumorigenesis
M Van der Toorn, K Baumer, D Peric, D Bornand, R Dulize, E Guedj, A Sewer, D Marescotti, K Luettich, NV Ivanov, M Peitsch, J Hoeng
-
Poster
March 16, 2018
Platform 1
Characterization of clones derived from human bronchial epithelial cells after long-term treatment with TPM from reference cigarettes versus THS 2.2
M Van der Toorn, M Sgandurra, D Marescotti, M Peitsch, J Hoeng, K Luettich
-
Poster
March 16, 2018
Systems Toxicology Assessment of Flavor Compounds Present in E-Vapor Products Using Human Primary Bronchial Epithelial Cells
D Marescotti, C Mathis, S Acali, V Belcastro, I Gonzalez-Suarez, S Frentzel, D Sciuscio, E Fernandes, M Biasoli, M Fuhrimann, F Frauendorfer, M Esposito, M Peitsch, J Hoeng
-
Poster
March 16, 2018
Human In Vitro Models for Respiratory Toxicology: Evaluation of Goblet Cell Hyperplasia, Mucus Production, and Ciliary Beating Assays
S Frentzel, M Aragon*, J Hoeng, S Ito*, S Ishikawa*, J Budde*, A Maione*, P Hayden*, W Fields*, B Keyser*, LE Haswell, D Azzopardi*, HP Behrsing *
* This author is not affiliated with PMI. -
Poster
March 9, 2018
Platform 1
Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic nasal epithelial cultures - a view from the proteome
C Nury, A Iskandar, B Titz, P Leroy, T Schneider, S Dijon, C Merg, C Mathis, A Elamin, S Frentzel, W Schlage, F Martin, NV Ivanov, M Peitsch, J Hoeng
-
Peer-Reviewed Publication
March 7, 2018
Platform 1
The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product
M Van der Toorn, A Sewer, D Marescotti, S Johne, K Baumer, D Bornand, R Dulize, C Merg, M Corciulo, E Scotti, C Pak, P Leroy, E Guedj, NV Ivanov, F Martin, M Peitsch, J Hoeng, K Luettich
DOI : 10.1016/j.tiv.2018.02.019
-
Peer-Reviewed Publication
March 1, 2018
Platform 2
Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment
A Iskandar, F Martin, P Leroy, W Schlage, C Mathis, B Titz, A Kondylis, T Schneider, G Vuillaume, A Sewer, E Guedj, K Trivedi, A Elamin, S Frentzel, NV Ivanov, M Peitsch, J Hoeng
DOI : 10.1016/j.fct.2018.02.063
-
Peer-Reviewed Publication
March 2, 2018
Platform 2
Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens
F Zanetti, A Sewer, E Scotti, B Titz, W Schlage, P Leroy, A Kondylis, G Vuillaume, A Iskandar, E Guedj, K Trivedi, T Schneider, A Elamin, F Martin, NV Ivanov, S Frentzel, M Peitsch, J Hoeng
DOI : 10.1016/j.fct.2018.02.062
-
Methods and Protocols
March 14, 2017
Platform 1
Analysis of ethylene oxide and vinyl chloride in THS aerosol
PMI
-
Methods and Protocols
March 14, 2017
Platform 1
Analysis of 12 polycyclic aromatic hydrocarbons in THS aerosol
PMI
-
Methods and Protocols
August 17, 2016
Platform 1
Procedure for accurately quantify water in mainstream aerosol of THS aerosol using the in situ extraction method
PMI
-
Poster
May 2, 2016
Platform 1
Lung Inflammation and Toxicological Assessment in A/J Mice in Response to Chronic Exposure to Mainstream Aerosol from Candidate Modified Risk Tobacco Product and Smoke from Conventional Cigarettes
E T Wong, K Luettich, K Trivedi, E Guedj, Y Xiang, A Elamin, E Veljkovic, AW Hayes, P Leroy, P Vanscheeuwijck, M Peitsch, J Hoeng
-
Poster
May 2, 2016
Platform 1
Xenobiotic Metabolism Responses of Nasal, Oral and Bronchial Organotypic Epithelial Cultures: A Comparison of Tobacco Heating System Aerosol and Combustible Cigarette Smoke
A Iskandar, S Majeed, L Ortega Torres, D Kuehn, S Johne, F Martin, Y Xiang, A Sewer, P Leroy, R Dulize, E Guedj, NV Ivanov, C Mathis, AW Hayes, J Hoeng, M Peitsch
-
Poster
March 20, 2015
Sytems toxicological-based assessment of sex-related differences in response to cigarette smoke within an OECD rat inhalation study
U Kogel, A Sewer, G Vuillaume, S Boue, M Talikka, E T Wong, WS Hayes, P Vanscheeuwijck, J Hoeng, M Peitsch
-
Poster
March 17, 2017
Modeling controlled deposition of polydisperse aerosol in 3D in-vitro exposure systems
F Lucci, A Kuczaj
-
Poster
March 12, 2017
Evaluation of Nicotine Pharmacokinetics and Subjective Effects following Use of a Novel Nicotine Aerosol System
Chris Wynne*, A Teichert, Patrick Brossard, Loyse Felber Medlin , Larissa Sandalic, J Ancerewicz, M Franzon, Murray Laugesen, F Lüdicke
* This author is not affiliated with PMI. -
Poster
March 12, 2017
Nicotine Population Pharmacokinetics in Healthy Adult Smokers
Patrick Brossard, M Marchand*, N Lama, R Weitkunat, H Merdjan*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
March 12, 2017
Intention to use the Tobacco Heating System, associated with variants of a potential product brochure
F Beacher, PP Magnani, A Ramazzotti, R Weitkunat, G Kallischnigg, S Colman*, T Alfieri*
* This author is not affiliated with PMI. -
Poster
February 27, 2018
Comparative effect of a candidate modified risk tobacco product aerosol and cigarette smoke on color stability of enamel, dentin and dental composite resins
F Zanetti, X Zhao, S Majeed, H Malmstrom*, M Peitsch, Y Ren*, J Hoeng
* This author is not affiliated with PMI. -
Poster
February 27, 2018
Prediction of disease-specific death rates by using forecasts of their key predictive ecological indicators
S Djurdjevic, A van der Plas, H Brenner*, G Baker, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 27, 2018
Psychometric evaluation of the mCEQ applied to cigarettes and heat-notburn products in the US and Japan
T Salzberger, S Cano, N Mainy, C Chrea, S Vandyke, C Haziza, R Weitkunat, Jed E Rose PhD*
* This author is not affiliated with PMI. -
Poster
February 26, 2018
Methodology for monitoring adverse event reports for potential modified risk tobacco products: experience at Philip Morris International
J Magnette, N Blanc, M Pietro, L Prieto, F Lüdicke
-
Poster
February 26, 2018
The relationship between intended use and perceived health risk for a novel heat-not-burn tobacco product
F Beacher, PP Magnani, G Kallischnigg, B Zwisele*, S Colman*, F Lüdicke, A Ramazzotti, R Weitkunat
* This author is not affiliated with PMI. -
Poster
February 26, 2018
Development of a tobacco and nicotine products dependence instrument
C Chrea, T Salzberger, L Abetz-Webb*, E Afolalu, S Cano, Jed E Rose PhD*, R Weitkunat, K Fagerström*
* This author is not affiliated with PMI. -
Poster
February 26, 2018
A multi-center multiregional study on biological and functional changes in healthy adult smokers during one year of continuous smoking abstinence
C Tran, Loyse Felber Medlin , N Lama, BV Taranu, E Pierri, J Ancerewicz, P Picavet, G Baker, C Haziza, F Lüdicke
-
Poster
February 26, 2018
Linguistic validation of the Perceived Risk Instrument (PRI) into French, German, Italian, Japanese, Polish and Russian
C Acquadro*, A Belay*, A Popielnicki*, N Mainy, R Weitkunat, C Chrea
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
February 16, 2018
Platform 1
Determination of eight carbonyl compounds in aerosols trapped in phosphate buffer saline solutions to support in vitro assessment studies
R Buratto, D Correia, M Parel, M Crenna, M Bilger, A Debrick
DOI : 10.1016/j.talanta.2018.02.048
-
Peer-Reviewed Publication
February 13, 2018
Platform 1
Assessment of mitochondrial function following short- and long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product and reference cigarettes
D Malińska*, J Szymanski*, P Patalas-Krawczyk*, B Michalska*, A Wojtala*, M Prill*, M Partyka*, K Drabik*, J Walczak*, A Sewer, S Johne, K Luettich, M Peitsch, J Hoeng, J Duszynski*, J Szczepanowska*, M Van der Toorn, M Wieckowski*
* This author is not affiliated with PMI.DOI : 10.1016/j.fct.2018.02.013
-
Poster
February 9, 2018
High-content screening-based phenotypic analysis of 3D organotypic bronchial tissues
D Marescotti, D Bovard, M Morelli, K Luettich, S Frentzel, M Peitsch, J Hoeng
-
Poster
February 5, 2018
Transcriptomic and metabolic analyses of 35S:S523DNR tobacco plants
L Bovet, J Lu*, JND Battey, RS Lewis, S Goepfert, RE Dewey*
* This author is not affiliated with PMI. -
Presentation
January 18, 2018
Platform 1
Nicotine biosynthesis pathway: beyond tobacco
M Kajikawa*, N Sierro, H Kawaguchi*, N Bakaher, NV Ivanov, T Hashimoto*, T Shoji*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
June 14, 2017
Platform 1
Systems Biology: Methods and Applications
B Titz, A Knorr, A Sewer, F Martin, NV Ivanov, M Talikka, I Gonzalez-Suarez, M Peitsch, J Hoeng
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
Pages 434–480
DOI : 10.1016/B978-0-12-409547-2.12333-9
-
Peer-Reviewed Publication
February 5, 2018
Organization of the TC and TE cT-DNA regions in Nicotiana otophora and functional analysis of three diverged TE-6b genes
K Chen*, F Dorlhac de Borne*, N Sierro, NV Ivanov, M Alouia*, S Koechler*, L Otten*
* This author is not affiliated with PMI.DOI : 10.1111/tpj.13853
-
Book Chapter
January 3, 2018
Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases 1st Edition
E Veljkovic, W Xia, B Phillips, E T Wong, J Ho, A Oviedo, J Hoeng, M Peitsch
-
Peer-Reviewed Publication
December 29, 2017
Platform 1
Accuracy of the Smoking Questionnaire
Z Sponsiello Wang, G de La Bourdonnaye, M David, F Lüdicke, R Weitkunat
Beiträge zur Tabakforschung International/Contributions to Tobacco Research
DOI : 10.1515/cttr-2017-0023
-
Peer-Reviewed Publication
December 29, 2017
Platform 1
Determination of Mercury in Aerosol by Inductively Coupled Plasma Mass Spectrometry
I Hofer, M Gremaud, A Marchese, S Le Bouhellec
Beiträge zur Tabakforschung International/Contributions to Tobacco Research
Volume 27, Issue 8, Pages 186–194
DOI : 10.1515/cttr-2017-0020
-
Peer-Reviewed Publication
January 9, 2018
Review of biomarkers to assess the effects of switching from cigarettes to modified risk tobacco products
M Peck, EB Sanders, G Scherer*, F Lüdicke, R Weitkunat
* This author is not affiliated with PMI.DOI : 10.1080/1354750X.2017.1419284
-
Peer-Reviewed Publication
December 28, 2017
Platform 1
Innovative methodology based on thermo-denuder principle for the detection of combustion related solid particles or high boiling point droplets: Applications to cigarette and the Tobacco Heating System THS 2.2
P Pratte, S Cosandey, C Goujon-Ginglinger
DOI : 10.1016/j.jaerosci.2017.12.011
-
Peer-Reviewed Publication
January 2, 2018
Platform 1
Effects of cigarette smoking on color stability of dental resin composites.
X Zhao, F Zanetti, S Majeed, J Pan*, H Malmstrom*, M Peitsch, J Hoeng, Y Ren*
* This author is not affiliated with PMI.American Journal of Dentistry.
30(6):316-322.
-
Peer-Reviewed Publication
December 13, 2017
Exploring the microbiome in health and disease: Implications for toxicology
E Scotti, S Boue, G Lo Sasso, F Zanetti, V Belcastro, C Poussin, N Sierro, JND Battey, A Gimalac, NV Ivanov, J Hoeng
Toxicology Research and Application
DOI : 10.1177/2397847317741884
-
Peer-Reviewed Publication
December 18, 2017
Platform 1
Quantifying the risk-reduction potential of new Modified Risk Tobacco Products
F Martin, G Vuillaume, G Baker, Z Sponsiello Wang, PF Ricci*, F Lüdicke, R Weitkunat
* This author is not affiliated with PMI.Regulatory Toxicology and Pharmacology
DOI : 10.1016/j.yrtph.2017.12.011
-
Presentation
December 5, 2017
Genetic Approaches and Resources for Enabling Compliance to Proposed NNN Standards
RE Dewey*, RS Lewis, J Lu*, L Bovet, S Goepfert, P Campanoni
* This author is not affiliated with PMI. -
Poster
December 5, 2017
Platform 1
Systems Toxicology meta-analysis: Impact of a candidate Modified-Risk Tobacco Product aerosol compared with cigarette smoke on organotypic aerodigestive tract cultures
A Iskandar, B Titz, A Sewer, P Leroy, T Schneider, F Zanetti, C Mathis, A Elamin, S Frentzel, W Schlage, F Martin, NV Ivanov, M Peitsch, J Hoeng
-
Poster
November 20, 2017
Platform 1
Genetic and Cell Toxicology In Vitro Assessment of Potentially Reduced Risk Products for Smokers
D McHugh, D Smart, G Cudazzo, P Vanscheeuwijck
-
Presentation
November 20, 2017
Platform 1
Pre-clinical and clinical studies in COPD and Cardiovascular areas and the Role of Biomarkers
JND Battey
-
Poster
September 14, 2017
Platform 1
Biomarker of Exposure Reductions Upon Switching for 5 Days From Cigarettes to a Carbon Heated Tobacco Product (CHTP 1.0)
C Tran, A Donelli, C Haziza, J Ancerewicz, G de La Bourdonnaye, R Weitkunat, F Lüdicke
-
Poster
November 16, 2017
Platform 1
Multiomics integration of transcriptomics, proteomics, and lipidomics for toxicological assessment
-
Peer-Reviewed Publication
November 9, 2017
Platform 1
Perplexing Conclusions Concerning Heat-Not-Burn Tobacco Cigarettes
-
Poster
October 20, 2017
Aerosol deposition in the human upper respiratory tract with different inhalation patterns
M Asgari, F Lucci, A Kuczaj
-
Poster
November 10, 2017
Platform 1
Using Rasch measurement to quantify the perceived risks associated with the use of tobacco and nicotine-containing products
C Chrea, S Cano, T Salzberger, T Alfieri*, N Mainy, A Ramazzotti, R Weitkunat, F Lüdicke
* This author is not affiliated with PMI. -
Poster
November 10, 2017
Platform 1
Measuring Changes in Patterns of Tobacco Product Use Over Time: Transition Probability Approaches
E. F. Afolalu, L Prieto, G de La Bourdonnaye, Z Sponsiello Wang, R Weitkunat
-
Presentation
October 25, 2017
Characterizing patterns of tobacco/nicotine-containing product use in the population
E. F. Afolalu
-
Presentation
October 25, 2017
Platform 1
Translational Biomarker Discovery & INTERVALS: A Platform Facilitating Transparent Data Sharing
A Elamin, D Page
-
Poster
October 25, 2017
Platform 1
Assessment of the Total Volatile Organic Compounds in Indoor Air During Use of the Tobacco Heating System 2.2
M Tharin, N Bielik, E G R Rouget, M Rotach, A Glabasnia
-
Poster
October 25, 2017
Platform 1
Psychometric Evaluation of the mCEQ applied to Cigarettes and Heat-Not-Burn Products in the US and Japan
T Salzberger, S Cano, N Mainy, C Chrea, S Vandyke, C Haziza, R Weitkunat, Jed E Rose PhD*
* This author is not affiliated with PMI. -
Methods and Protocols
April 3, 2017
Platform 1
Determination of Glycerin and Menthol in THS aerosol
PMI
-
Methods and Protocols
October 15, 2016
Aerosol Droplet Size Distribution Measurement Instruments
PMI
-
Methods and Protocols
March 22, 2017
Platform 1
Analysis of acetamide and acrylamide in THS aerosol
PMI
-
Presentation
October 16, 2017
Platform 1
Air Quality Assessment during Indoor Use of the Tobacco Heating System THS 2.2
-
Poster
October 16, 2017
Platform 1
How Do Consumers Use the Candidate Modified Risk Tobacco Product (MRTP): Tobacco Heating System (THS): Analysis of Data from Six Countries
S Roulet, PP Magnani, G Kallischnigg, S Badoglio, K Ackermann, M Veit, Ariella Dugan*, Chris Gage*, Claudia Kanitscheider*, Mercedes Apecechea*, A Ramazzotti
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
September 28, 2017
Platform 1
Comparative effects of a candidate modified-risk tobacco product aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach
A Iskandar, Y Martinez, F Martin, W Schlage, P Leroy, A Sewer, L Ortega Torres, S Majeed, C Merg, K Trivedi, E Guedj, S Frentzel, C Mathis, NV Ivanov, M Peitsch, J Hoeng
-
Peer-Reviewed Publication
September 25, 2017
Eulerian modeling of inertial and diffusional aerosol deposition in bent pipes
EM Frederix*, A Kuczaj, M Nordlund, AEP Veldman*, BJ Geurts*
* This author is not affiliated with PMI. -
Poster
May 12, 2016
Platform 1
Absence of Combustion in an Electrically Heated Tobacco System - An Experimental Investigation
V Cozzani*, T McGrath, M Smith, JP Schaller, G Zuber
* This author is not affiliated with PMI. -
Poster
September 28, 2017
Platform 1
Exposure to Cigarette Smoke and Aerosol from the Candidate Modified Risk Tobacco Product THS2.2 on A/J Mice in a Life-Time Inhalation Study
E T Wong, K Luettich, E Guedj, R Dulize, C Nury, B Titz, P Leroy, G Vuillaume, A Elamin, NV Ivanov, E Veljkovic, P Vanscheeuwijck, M Peitsch, J Hoeng
-
Poster
September 22, 2017
Platform 1
Proteomics as Part of a Multi-Omics Systems Toxicological Assessment of a Mentholated Candidate Modified Risk Tobacco Product
C Nury, U Kogel, B Titz, W Schlage, F Martin, A Oviedo, S Lebrun, A Elamin, E Guedj, K Trivedi, NV Ivanov, P Vanscheeuwijck, M Peitsch, J Hoeng
-
Poster
September 22, 2017
Heated Tobacco Products
Quantitative Proteomics to Investigate the Effects of a Prototype Modified Risk Tobacco Product (pMRTP) and Smoking Cessation on Mouse Lung Proteome.
S Dijon, A Elamin, B Titz, C Merg, M Geertz, T Schneider, F Martin, W Schlage, S Frentzel, F Talamo, E Veljkovic, NV Ivanov, P Vanscheeuwijck, M Peitsch, J Hoeng
-
Poster
September 22, 2017
Platform 1
Integration of Targeted Proteomics into Systems Toxicology Approach: Candidate Modified-Risk Tobacco Product Assessment using Nasal Cultures
T Schneider, A Elamin, A Iskandar, F Zanetti, C Merg, A Sewer, B Titz, P Leroy, E Guedj, S Majeed, L Ortega Torres, W Schlage, C Mathis, F Martin, S Frentzel, NV Ivanov, M Peitsch, J Hoeng
-
Poster
September 19, 2017
Platform 1
Systems Biology Verification Project: Past, Present, and Future.
-
Poster
September 20, 2017
Platform 1
Systems Toxicology Meta-Analysis: Impact of a Candidate Modified-Risk Tobacco Product Aerosol compared with Cigarette Smoke on Organotypic Aerodigestive Tract Cultures
A Iskandar, B Titz, A Sewer, P Leroy, T Schneider, F Zanetti, C Mathis, A Elamin, S Frentzel, W Schlage, F Martin, NV Ivanov, M Peitsch, J Hoeng
-
Poster
September 20, 2017
Platform 1
Air Quality Assessment during Indoor Use of the Tobacco Heating System THS 2.2
-
Poster
September 20, 2017
Platform 1
Assessment of Mitochondrial Function Following Long-Term Treatment of Human Bronchial Epithelial Cells with Total Particulate Matter from a Candidate Modified Risk Tobacco Product versus Cigarettes
M Van der Toorn, D Malińska*, J Szymanski*, J Walczak*, M Prill*, K Drabik*, B Michalska*, A Wojtala*, P Patalas-Krawczyk*, M Partyka*, S Johne, A Sewer, E Guedj, K Luettich, M Peitsch, J Hoeng, M Wieckowski*, J Szczepanowska*, J Duszynski*
* This author is not affiliated with PMI. -
Poster
September 20, 2017
Platform 1
Systems Toxicology Assessment of Repeated Exposure to Cigarette Smoke and a Candidate Modified-Risk Tobacco Product Aerosol on Gingival Organotypic Cultures
F Zanetti, A Sewer, P Leroy, S Majeed, L Ortega Torres, C Merg, M Corciulo, K Trivedi, E Guedj, A Elamin, S Frentzel, NV Ivanov, M Peitsch, J Hoeng
-
Poster
September 4, 2017
Platform 1
In Vitro Systems Toxicology Assessment of Exposure to Aerosol from a Carbon Heated Tobacco Product as Compared with Exposure to Cigarette Smoke: The Impact on Nasal and Small Airway Epithelial Cultures
A Iskandar, Y Martinez, C Mathis, P Leroy, F Martin, A Sewer, L Ortega Torres, S Majeed, K Trivedi, S Frentzel, E Guedj, C Merg, A Elamin, NV Ivanov, M Peitsch, J Hoeng
-
Peer-Reviewed Publication
August 21, 2017
Organs-on-a-chip: A new paradigm for toxicological assessment and preclinical drug development
-
Peer-Reviewed Publication
June 6, 2017
Novel approaches to develop community-built biological network models for potential drug discovery
M Talikka, N Bukharov, WS Hayes, M Hofmann-Apitius*, L Alexopoulos*, M Peitsch, J Hoeng
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
September 5, 2017
Platform 4
Toxicity of the Main Electronic Cigarette Components, Propylene Glycol, Glycerin, and Nicotine, in Sprague-Dawley Rats in a 90-Day OECD Inhalation Study Complemented by Molecular Endpoints
B Phillips, B Titz, U Kogel, D Sharma, P Leroy, Y Xiang, G Vuillaume, S Lebrun, D Sciuscio, J Ho, C Nury, E Guedj, A Elamin, M Esposito, AS Krishnan *, W Schlage, E Veljkovic, NV Ivanov, F Martin, M Peitsch, J Hoeng, P Vanscheeuwijck
* This author is not affiliated with PMI. -
Presentation
September 5, 2017
Platform 4
Online Aerosol Analysis Using FTIR: Assessing Carbonyl Yields in E-Cigarette Aerosol
-
Poster
September 5, 2017
Platform 4
Novel FITR Online Method for E-Cigarette Aerosol Characterization
F Radtke, R Monni, A Susz, A Stoop, J Verbeeck, S Maeder
-
Poster
September 5, 2017
Absorption Efficiency of Particulate and Gaseous Aerosol Constituents at Aqueous Surfaces
S Steiner, P Diana, E Dossin, P Guy, G Vuillaume, A Kondylis, S Majeed, S Frentzel, J Hoeng
-
Poster
March 22, 2017
Recent Improvements of the BEL Information Extraction workFlow (BELIEF) for Biomedical Text Mining and Curation
J Hoeng, M Peitsch, M Talikka, J Fluck*, J Doerpinghaus*, AW Hayes, S Madan*, J Szostak
* This author is not affiliated with PMI. -
Poster
March 17, 2017
The Adverse Outcome Pathway for Mucus Hypersecretion in Chronic Bronchitis
K Luettich, M Talikka, FJ Lowe*, LE Haswell, J Szostak, F Martin, M Gaca*, J Hoeng
* This author is not affiliated with PMI. -
Presentation
July 27, 2017
Harness the Power of the Crowd to Address Computational and Biological Challenges
V Belcastro, S Boue
-
Presentation
July 7, 2017
Alterations of the Sputum Proteome and Transcriptome and Serum Lipidome from Smokers and Early-Stage COPD Subjects
T Schneider
-
Presentation
July 7, 2017
Proteomics for Systems Toxicology
-
Presentation
May 5, 2017
Impact of cigarette smoke and Modified Risk Tobacco Products (MRTPs) on DNA methylation
A Choukrallah
-
Presentation
May 5, 2017
sbv IMPROVER Epigenomics Challenge
N Sierro
-
Presentation
May 30, 2017
Investigator-Initiated Studies (IIS) in Non-Pharma Industries
-
Peer-Reviewed Publication
July 14, 2017
Platform 1
The sbv IMPROVER Systems Toxicology computational challenge: Identification of human and species-independent blood response markers as predictors of smoking exposure and cessation status
V Belcastro, C Poussin, Y Xiang, M Giordano*, KP Tripathi*, A Boda, AT Balci*, I Bilgen*, SD Dhanda*, Z Duan*, X Gong*, R Kumar*, R Romero*, OS Sarac*, AL Tarca*, P Wang*, H Yang*, W Yang*, S Boue, C Zhang*, MR Guarracino*, F Martin, M Peitsch, J Hoeng
* This author is not affiliated with PMI.DOI : 10.1016/j.comtox.2017.07.004
-
Presentation
June 16, 2017
Heated Tobacco Products
The Importance of offering Adult Smokers a Portfolio of Potentially Less Harmful Products
T McGrath
-
Presentation
June 16, 2017
Heated Tobacco Products
Heated Tobacco Technology: Science, Behavior and Avoiding Unintended Consequences
-
Poster
August 25, 2017
Platform 1
Assessment of Mitochondrial Function Following Long-Term Treatment of Human Bronchial Epithelial Cells with Total Particulate Matter from a candidate Modified-Risk Tobacco Product versus Cigarettes
M Van der Toorn, D Malińska*, J Szymanski*, J Walczak*, M Prill*, K Drabik*, B Michalska*, A Wojtala*, P Patalas-Krawczyk*, M Partyka*, S Johne, A Sewer, E Guedj, K Luettich, M Peitsch, J Hoeng, M Wieckowski*, J Szczepanowska*, J Duszynski*
* This author is not affiliated with PMI. -
Poster
August 25, 2017
Nicotine-Containing E-Vapor Products
3D vasculature-on-a-chip: a model of perfused human coronary artery endothelial microvessel for studying monocyte to endothelium adhesion under flow
C Poussin, V van Duinen*, HL Lanz*, A van den Heuvel*, Kramer B*, A Laurent, M Van der Toorn, M Peitsch, J Hoeng, J Joore*
* This author is not affiliated with PMI. -
Infoposter
June 16, 2017
Platform 1
Post-market assessment of the Tobacco Heating System 2.2 (THS) use in Japan
L Prieto, A van der Plas, D Skiada, M Benzimra, M Dobrynina, D Tudor, R Weitkunat, F Lüdicke
-
Infoposter
June 16, 2017
Platform 1
Perceived health risk of the Tobacco Heating System and comparators, associated with variants of a potential product brochure
F Beacher, PP Magnani, A Ramazzotti, R Weitkunat, G Kallischnigg, S Colman*, T Alfieri*
* This author is not affiliated with PMI. -
Infoposter
June 16, 2017
Platform 1
Intention to use the Tobacco Heating System, associated with variants of a potential product brochure
F Beacher, PP Magnani, A Ramazzotti, R Weitkunat, G Kallischnigg, S Colman*, T Alfieri*
* This author is not affiliated with PMI. -
Infoposter
June 16, 2017
Platform 2
Biomarker of exposure reductions upon switching for 5 days from cigarettes to a carbon heated tobacco product (CHTP 1.0)
A Donelli, C Tran, C Haziza, J Ancerewicz, G de La Bourdonnaye, R Weitkunat, F Lüdicke
-
Infoposter
June 16, 2017
Platform 1
Actual use study of the Potential Reduced-Risk Product (RRP): Tobacco Heating System (THS)
S Roulet, PP Magnani, G Kallischnigg, Ariella Dugan*, Chris Gage*, Claudia Kanitscheider*, Mercedes Apecechea*, A Ramazzotti
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
August 14, 2017
Platform 1
Comparative assessment of HPHC yields in the Tobacco Heating System THS2.2 and commercial cigarettes
G Jaccard, D Tafin Djoko, O Moennikes, C Jeannet, A Kondylis, M Belushkin
-
Data
December 16, 2016
Platform 1
Atherogenesis study in vitro - Transendothelial assay of monocytic cells to endothelial cells with THS2.2
PMI
-
Data
December 16, 2016
Platform 1
Assessment of repeated THS2.2 aerosol exposure in in vitro Human gingival epithelial cultures
PMI
-
Data
December 16, 2016
Platform 1
Assessment of acute THS2.2 aerosol exposure in in vitro Human bronchial epithelial cultures
PMI
-
Data
December 16, 2016
Platform 1
Assessment of acute THS2.2 aerosol exposure in in vitro Human buccal epithelial cultures
PMI
-
Poster
June 14, 2010
Simulation Of Impaction Filtration Of Aerosol Droplets In Porous Media
S Stolz, BJ Geurts*, DJ Lopez Penha, L Ghazaryan*
* This author is not affiliated with PMI. -
Poster
September 21, 2016
Nicotine-Containing E-Vapor Products
Determination of Leakage in E-vaping Products
J Thomas, H Goksel
-
Peer-Reviewed Publication
July 29, 2017
Platform 1
Nicotine pharmacokinetic profiles of the Tobacco Heating System 2.2, cigarettes and nicotine gum in Japanese smokers
Patrick Brossard, R Weitkunat, V Poux, N Lama, C Haziza, P Picavet, G Baker, F Lüdicke
-
Data
December 16, 2016
Platform 1
Assessment of acute THS2.2 aerosol exposure in in vitro Human nasal epithelial cultures
PMI
-
Data
December 16, 2016
Platform 1
8-month systems toxicology inhalation / cessation study with THS2.2 in Apoe‑/‑ mice
PMI
-
Peer-Reviewed Publication
July 2, 2009
Lung Inflammation In Rats Following Subchronic Exposure To Cigarette Mainstream Smoke
B Friedrichs, E Van Miert, P Vanscheeuwijck
-
Peer-Reviewed Publication
June 29, 2017
Simulation of aerosol formation due to rapid cooling of multispecies vapors
C Winkelmann, A Kuczaj, M Nordlund, BJ Geurts*
* This author is not affiliated with PMI.Journal of Engineering Mathematics
DOI : 10.1007/s10665-017-9918-6
-
Poster
March 5, 2006
Effects of Aqueous Solutions of Cigarette Mainstream Smoke on the Norepinephrine-Induced Contraction of Rat Aortic Rings in Vitro
T Wallerath, K Von Holt, R Schleef*
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
August 15, 2006
Estimating Preventable Fractions of Disease Caused by a Specified Biological Mechanism: PAHs in Smoking Lung Cancers as an Example
LA Cox Jr*, EB Sanders
* This author is not affiliated with PMI. -
Book Chapter
July 7, 2017
Heated Tobacco Products
Consumer Perception of Product Risks and Benefits
G Emilien, R Weitkunat, F Lüdicke
-
Peer-Reviewed Publication
June 24, 2017
Estimating the effect of differing assumptions on the population health impact of introducing a Reduced-Risk Tobacco Product in the USA
PN Lee*, JS Fry*, JF Hamling*, Z Sponsiello Wang, G Baker, R Weitkunat
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
June 5, 2017
Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal Epithelium
M Talikka, F Martin, A Sewer, G Vuillaume, P Leroy, K Luettich, N Chaudhary, M Peck, M Peitsch, J Hoeng
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine
Volume 11: 1–11
DOI : 10.1177/1179548417710928
-
Peer-Reviewed Publication
April 28, 2017
Studies on the contributions of smoke constituents, individually and in mixtures, in a range of in vitro bioactivity assays
R Stabbert, R Dempsey, J Diekmann, C Euchenhofer, T Hagemeister, HJ Haussmann, A Knorr, BP Muller*, P Pospisil, W Reininghaus, E Roemer, FJ Tewes, D Veltel
* This author is not affiliated with PMI.DOI : 10.1016/j.tiv.2017.04.003
-
Report
October 2, 2017
Platform 1
The Science behind the Tobacco Heating System -- A summary of published scientific articles
M Smith, C Haziza, J Hoeng, F Lüdicke, S Maeder, P Vanscheeuwijck, M Peitsch
-
Poster
March 8, 2017
Modeling the impact of changes in tobacco use on individual disease risk
R Weitkunat, F Lüdicke, JS Fry*, PN Lee*, S Djurdjevic, Z Sponsiello Wang, G Baker
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
April 27, 2017
Nicotine-Containing E-Vapor Products
Characterization of the Vitrocell® 24/48 aerosol exposure system for its use in exposures to liquid aerosols
S Steiner, S Majeed, G Kratzer, G Vuillaume, J Hoeng, S Frentzel
DOI : 10.1016/j.tiv.2017.04.021
-
Peer-Reviewed Publication
March 10, 2017
Platform 1
Nicotine Population Pharmacokinetics in Healthy Adult Smokers: A Retrospective Analysis
M Marchand*, Patrick Brossard, H Merdjan*, N Lama, R Weitkunat, F Lüdicke
* This author is not affiliated with PMI.European Journal of Drug Metabolism and Pharmacokinetics
DOI : 10.1007/s13318-017-0405-2
-
Scientific Dossier
April 1, 2017
Platform 1
Intent to Use for a New Menthol HeatSticks Variant in Japan
A Ramazzotti, S Badoglio, H Wilson*, F Beacher, PP Magnani
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
May 4, 2017
Multicomponent aerosol particle deposition in a realistic cast of the human upper respiratory tract
M Nordlund, M Belka*, A Kuczaj, F Lizal*, J Jedelsky*, J Elcner*, M Jicha*, Y Sauser, S Le Bouhellec, S Cosandey, S Majeed, G Vuillaume, M Peitsch, J Hoeng
* This author is not affiliated with PMI.DOI : 10.1080/08958378.2017.1315196
-
Peer-Reviewed Publication
January 4, 2017
Platform 1
Biomarker of exposure level data set in smokers switching from conventional cigarettes to Tobacco Heating System 2.2, continuing smoking or abstaining from smoking for 5 days
C Haziza, G de La Bourdonnaye, D Skiada, J Ancerewicz, G Baker, P Picavet, F Lüdicke
DOI : 10.1016/j.dib.2016.11.047
-
Peer-Reviewed Publication
February 8, 2017
Platform 1
Effects of Switching to Menthol THS2.2, Smoking Abstinence, or Continued Cigarette Smoking on Clinically Relevant Risk Markers: A Randomized, Controlled, Open-Label, Multicenter Study in Sequential Confinement and Ambulatory Settings (Part 2)
F Lüdicke, P Picavet, G Baker, C Haziza, V Poux, N Lama, R Weitkunat
DOI : 10.1093/ntr/ntx028
-
Methods and Protocols
December 11, 2014
In Vivo Toxicology and the assessment of Reduced-Risk Productsmore information
PMI
-
Methods and Protocols
December 11, 2014
In Vivo Exposure Systems and the assessment of Reduced-Risk Products
PMI
-
Methods and Protocols
December 11, 2014
Overview of in vitro assays used in the standard toxicological assessment of Reduced-Risk Products
PMI
-
Poster
March 1, 2017
Platform 1
Candidate MRTP Aerosol has Low Impact on Organotypic Gingival Cultures
F Zanetti, B Titz, A Sewer, G Lo Sasso, E Scotti, W Schlage, C Mathis, P Leroy, S Majeed, L Ortega Torres, BR Keppler*, A Elamin, K Trivedi, E Guedj, S Frentzel, NV Ivanov, M Peitsch, J Hoeng
* This author is not affiliated with PMI. -
Poster
March 1, 2017
Platform 1
Comparative systems toxicology assessment of aerosol from a candidate modified risk tobacco product and cigarette smoke in organotypic human gingival epithelial cultures
F Zanetti, B Titz, A Sewer, G Lo Sasso, E Scotti, W Schlage, C Mathis, P Leroy, S Majeed, L Ortega Torres, BR Keppler*, A Elamin, K Trivedi, E Guedj, F Martin, S Frentzel, NV Ivanov, M Peitsch, J Hoeng
* This author is not affiliated with PMI. -
Peer-Reviewed Publication
May 29, 2017
Platform 1
Systems Toxicology Meta-Analysis of In Vitro Assessment Studies: Biological Impact of a Candidate Modified-Risk Tobacco Product Aerosol Compared with Cigarette Smoke on Human Organotypic Cultures of the Aerodigestive Tract
A Iskandar, B Titz, A Sewer, P Leroy, T Schneider, F Zanetti, C Mathis, A Elamin, S Frentzel, W Schlage, F Martin, NV Ivanov, J Hoeng, M Peitsch
-
Presentation
June 16, 2017
Platform 1
What is combustion and why the absence of combustion is important in Heated Tobacco Products?
T McGrath
-
Infoposter
June 16, 2017
Platform 3
Evaluation of nicotine pharmacokinetics and subjective effects following use of a novel nicotine aerosol system
F Lüdicke, Murray Laugesen, Chris Wynne*, M Franzon, J Ancerewicz, Larissa Sandalic, Loyse Felber Medlin , Patrick Brossard, A Teichert
* This author is not affiliated with PMI. -
Poster
September 13, 2011
Wisdom of Crowds for Diagnostics Signature Challenge
J Hoeng, M Talikka, P Meyer*, R Norel*, JJ Rice*, J Sprengel*, G Stolovitzky, M Peitsch
* This author is not affiliated with PMI. -
Poster
July 19, 2013
Verification Of Systems Biology Research: Species Translation And Biological Networks
E Bilal*, J Binder, S Boue, B Fields*, AW Hayes, A Iskandar, R Kleiman*, P Meyer*, R Norel*, J Park*, C Poussin, K Rhrissorrakrai*, JJ Rice*, J Sprengel*, M Talikka, G Stolovitzky, J Hoeng
* This author is not affiliated with PMI. -
Poster
September 15, 2013
Verification Of Systems Biology Research In The Age Of Collaborative- Competition: Biological Network Models
S Ansari, E Bilal*, J Binder, S Boue, P Curle, B Fields*, AW Hayes, J Hoeng, A Iskandar, R Norel*, M Peitsch, C Poussin, JJ Rice*, P Meyer*, K Rhrissorrakrai*, G Stolovitzky, M Talikka
* This author is not affiliated with PMI. -
Poster
February 3, 2014
Verification of Systems Biology Research In The Age Of Collaborative Competition: Biological Network Models
S Ansari, E Bilal*, J Binder, S Boue, P Curle, B Fields*, AW Hayes, J Hoeng
* This author is not affiliated with PMI. -
Poster
March 17, 2014
Verification Of Systems Biology Research In The Age Of Collaborative Competition
E Bilal*, J Binder, E Blaese*, S Boue, M Charaf, P Curle, B Fields*, C Frei*, AW Hayes, A Iskandar, R Kleiman*, I Luhn*, P Meyer*, R Norel*, J Park*, C Poussin, K Rhrissorrakrai*, JJ Rice*, A Scotland, M Talikka, J Taylor, G Stolovitzky, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
March 23, 2015
Verification of Causal Biological Networks Using a Web-based Collaborative Competition
S Ansari, V Belcastro, S Boue, L Cannesson, M Costa, A Ertan, B Fields*, AW Hayes, J Hoeng, NV Ivanov, F Martin, D Page, J Park*, M Peitsch, C Poussin, M Talikka
* This author is not affiliated with PMI. -
Poster
July 19, 2010
Validation of the in vitro comet assay in conjunction with an air‐liquid interface exposure of cigarette smoke in human lung epithelial cells
S Weber, M Hebestreit, T Wilms, B Kurkowsky
-
Poster
June 17, 2016
Platform 1
Validating PMI’s Population Health Impact Model
G Baker, Z Sponsiello Wang, PN Lee*, JS Fry*, F Lüdicke, R Weitkunat
* This author is not affiliated with PMI. -
Poster
October 5, 2014
Using an iTRAQ Approach to Investigate the Effect of Cigarette Smoke Exposure in a 90-day Inhalation Study Followed by 42-days Recovery Period on Sprague-Dawley Rats Lung Tissues
A Elamin, T Schneider, S Dijon, E T Wong, B Titz, F Martin, U Kogel, P Vanscheeuwijck, NV Ivanov, J Hoeng, M Peitsch
-
Poster
September 14, 2013
Using 2D-PAGE And iTRAQ Proteomics Approaches To Investigate The Effect Of Cigarette Smoke Fraction Exposure On Primary Normal Human Bronchial Epithelial (NHBE) Cells
E Martin, S Dijon, T Schneider, F Martin, S Wagner, U Kogel, F Talamo, C Mathis, J Hoeng, P Vanscheeuwijck, M Peitsch
-
Poster
September 29, 2006
Urinary Excretion of Ethenoadenine and Ethenocytosine by Smokers and Nonsmokers
G Scherer*, G Gilch*, HW Hagedorn*, A R Tricker
* This author is not affiliated with PMI. -
Poster
January 21, 2016
Platform 4
Transfer Rate Assessment for Eight Selected Flavors in e-Liquid Using GC-Q-TOF-MS and Mass Profiler Professional Software
E Dossin, P Diana, M Bentley, P Guy
-
Poster
November 10, 2015
Toxicological evaluation of the Tobacco Heating System 2.2, a candidate Modified Risk Tobacco Product in a 90-Day OECD inhalation study complemented with systems toxicology
U Kogel, E T Wong, B Titz, S Boue, A Elamin, G Vuillaume, P Leroy, NV Ivanov, G Rodrigo, E Veljkovic, J Hoeng, P Vanscheeuwijck, M Peitsch
-
Poster
February 26, 2015
Platform 3
Toxicity Of Inhaled Nicotine And Pyruvic Acid Aerosols (Separately And Combined) In Sprague-Dawley Rats In A 28-Day OECD TG412 Inhalation Study
M Esposito, B Phillips, P Vanscheeuwijck, A Buettner*, J Hoeng, W Schlage, J Verbeeck, M Peitsch
* This author is not affiliated with PMI. -
Poster
November 9, 2008
Towards A Mouse Inhalation Model For Tobacco Smoke-Induced Lung Tumorigenesis
W Stinn, J Arts*, A Buettner*, B Friedrichs, S Gebel*, R Weitkunat, F van Overveld, HJ Haussmann
* This author is not affiliated with PMI. -
Poster
December 15, 2009
Time-Course Of Airway Responsiveness And Inflammatory Mediator Release In Precision-Cut Lung Slices From Cigarette-Smoke-Exposed A/J Mice
V Simoen, K Vandevelde , K Jonckers, E Matthijis, M Peck, A Wohlsen
-
Poster
September 26, 2010
Time- And Concentration-Dependent Effects Of Cigarette Smoke On Monocytic Cell Transcriptome
-
Poster
May 20, 2007
The role of cigarette smoke-induced gene expression modifications in the etiogenesis of lung cancer
E Veljkovic, A Anstett*, H Rehrauer*, G Marra*, W Han, J Jiricny*
* This author is not affiliated with PMI. -
Poster
February 27, 2015
The Perceived Risk Instrument (PRI) To Measure Perceived Risks Associated With The Use Of Nicotine And Tobacco Products
C Chrea, G Emilien, T Salzberger, S Cano, T Alfieri*, N Mainy, A Ramazzotti, R Weitkunat, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 26, 2015
Heated Tobacco Products
The Impact Of Switching To pMRTP On The Development Of Cigarette Smoke - Induced COPD In C57Bl/6 Mice
E Veljkovic, B Phillips, M Peck, A Buettner*, G Vuillaume, S Boue, F Martin, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
April 14, 2016
Heated Tobacco Products
The BEL Information Extraction Workflow (BELIEF): Updates and Evaluation poster
S Ansari, S Madan*, J Szostak, P Senger*, M Talikka, J Fluck*, J Hoeng
* This author is not affiliated with PMI. -
Poster
July 1, 2013
Platform 2
Systems Toxicology In ApoE-/- Mice Demonstrates Similar Benefits Of Switch To pMRTP And Smoking Cessation For Both Cardiovascular And Lung Disease-Related Endpoints
S Boue, H De Leon, S Lebrun, W Schlage, G Vuillaume, F Martin, J Hoeng, M Peitsch
-
Poster
March 14, 2016
Platform 1
Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Compared to a Combustible Cigarette
I Gonzalez-Suarez, F Martin, D Marescotti, E Guedj, S Acali, S Johne, R Dulize, K Baumer, D Peric, D Goedertier, S Frentzel, NV Ivanov, C Mathis, AW Hayes, J Hoeng, M Peitsch
-
Poster
June 30, 2013
Systems Toxicology Approaches Enable Mechanistic Comparison Of Cigarette Smoke-Induced And Spontaneous Lung Tumors In The A/J Mouse Model
A Iskandar, Y Xiang, A Sewer, K Luettich, F Martin, M Talikka, P Vanscheeuwijck, E Veljkovic, I Gonzalez-Suarez, J Hoeng, M Peitsch
-
Poster
March 23, 2014
Platform 2
Systems Toxicology Approach For The Biological Impact Assessment Of Conventional Cigarette Smoke Fractions And Aerosol Fractions From A Prototypic Modified Risk Tobacco Product On Normal Human Bronchial Epithelial Cells
U Kogel, Y Xiang, E Dossin, P Guy, C Mathis, I Gonzalez-Suarez, G Vuillaume, AW Hayes, J Hoeng, M Peitsch
-
Poster
July 1, 2016
Platform 1
Systems toxicology analysis of cardiovascular and respiratory endpoints from ApoE-/- mice showed similar effects when switching to a candidate Modified Risk Tobacco Product, THS2.2, or ceasing smoking
B Phillips, E Guedj, A Elamin, S Boue, G Vuillaume, F Martin, P Leroy, N Sierro, AW Hayes, E Veljkovic, NV Ivanov, M Peitsch, J Hoeng
-
Poster
February 26, 2015
Heated Tobacco Products
Systems Toxicology Analysis Of Cardiovascular And Respiratory Endpoints-From ApoE-/- Mice Showed Similar Effects After Switching To A Candidate Modified-Risk-Tobacco Product, THS 2.2: Or To Smoking Cessation
B Phillips, H De Leon, M Cabanski, S Boue, G Vuillaume, F Martin, P Leroy, E Veljkovic, M Peitsch, J Hoeng
-
Poster
February 26, 2015
Heated Tobacco Products
Systems Toxicology Analysis Of Cardiovascular And Respiratory Endpoints From ApoE-/- Mice Showed Similar Effects After Switching To A Candidate Modified Risk Tobacco Product: THS 2.2, Or To Smoking Cessation
B Phillips, H De Leon, M Cabanski, S Boue, G Vuillaume, F Martin, P Leroy, E Veljkovic, M Peitsch, J Hoeng
-
Poster
March 23, 2015
Platform 1
Systems toxicology analysis of cardiovascular and respiratory endpoints from Apoe-/- mice showed similar effects after switching to a candidate modified risk tobacco product, THS 2.2, or to smoking cessation-
B Phillips, S Boue, G Vuillaume, F Martin, P Leroy, E Veljkovic, M Peitsch, J Hoeng
-
Poster
November 10, 2015
Heated Tobacco Products
Systems toxicology analysis of cardiovascular and respiratory endpoints from Apoe-/- mice showed similar effects after switching to a candidate modified risk tobacco product, THS 2.2, or to smoking cessation
B Phillips, E Veljkovic, S Boue, W Schlage, G Vuillaume, F Martin, B Titz, P Leroy, A Buettner*, A Elamin, M Cabanski, E Guedj, M Talikka, NV Ivanov, P Vanscheeuwijck, M Peitsch, J Hoeng
* This author is not affiliated with PMI. -
Poster
January 29, 2016
Heated Tobacco Products
Systems biology verification: the systems toxicology challenge and transparent toxicology via enhanced review platform
S Boue, C Poussin, V Belcastro, A Ertan, F Martin, D Page, L Cannesson, B Titz, M Peitsch, J Hoeng
-
Poster
September 1, 2013
Systems Biology Approach Reveals A Dose-Dependent Recovery Of Primary Human Airway Epithelium Culture After Exposure To Cigarette Smoke
C Mathis, S Gebel*, C Poussin, D Weisensee, A Sewer, V Belcastro, S Ansari, M Cabanski, S Wagner, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
June 24, 2008
Systematic review of the relation between smokeless tobacco and cancer of the pancreas in Europe and North America
Z Sponsiello Wang, R Weitkunat, PN Lee*
* This author is not affiliated with PMI. -
Poster
March 3, 2016
Heated Tobacco Products
Study to Quantitatively Assess Tobacco Heating System 2.2 Potential Messages
F Beacher, PP Magnani, A Ramazzotti, R Weitkunat, G Kallischnigg, S Colman*, T Alfieri*
* This author is not affiliated with PMI. -
Poster
January 14, 2017
Heated Tobacco Products
Study To Assess Tobacco Heating System 2.2 Potential Messages
F Beacher, PP Magnani, A Ramazzotti, R Weitkunat, G Kallischnigg, S Colman*, T Alfieri*
* This author is not affiliated with PMI. -
Poster
June 9, 2013
Sensitive Quantification Of Key Oxysterols In Biological Matrix Using High Resolution Accurate Mass Spectrometry
D Arndt, S Della Gatta, M Bentley
-
Poster
September 17, 2013
Platform 1
Screening Of Aqueous Media Using GC×GC-TOF-MS
M Almstetter, A Knorr, A Debrick , Q Dutertre, M Bentley
-
Poster
April 7, 2016
Heated Tobacco Products
Scientific Computing Infrastructure for Systems Toxicology
-
Poster
March 18, 2013
SBV Improver: The Species Translation Challenge
C Poussin, V Belcastro, E Bilal*, C Mathis, R Norel*, P Meyer*, JJ Rice*, J Sprengel*, G Stolovitzky, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
May 30, 2016
Heated Tobacco Products
Retention Index Prediction Combined with in silico Fragmentation Spectra Comparison for Increasing Confidence in Structural Elucidation Using Non-targeted Gas Chromatography Coupled with High Resolution Mass Spectrometry
P Guy, E Dossin, E Martin, P Diana, P Pospisil, M Bentley
-
Publication
October 24, 2005
Heated Tobacco Products
Reductions In Exposure To Certain Cigarette Smoke Constituents After Switching From A Conventional Cigarette To Electrically Heated Cigarette Smoking Systems
C Martin Leroy, J Diekmann, D Lindner, A R Tricker, H Bleisath
-
Poster
September 30, 2014
Reduced Impact of a Prototypic Modified Risk Tobacco Product Compared with Conventional Cigarette Smoke on Exposed Human and Rat Primary Normal Bronchial Epithelial Cells
C Mathis, U Kogel, DE Messinis *, C Poussin, F Martin, S Frentzel, E Guedj, NV Ivanov, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Heated Tobacco Products
Reduced Exposure To Harmful And Potentially Harmful Constituents After Five Days Of Use Of tobacco Heating System 2.2: A Comparison With Continued Combustible Cigarette Use Or Smoking Abstinence [Japan]
C Haziza, G de La Bourdonnaye, G Baker, M Benzimra, J Ancerewicz, P Picavet, F Lüdicke
-
Poster
March 23, 2015
Heated Tobacco Products
Reduced Exposure To Harmful And Potentially Harmful Constituents After Five Days of Use of Tobacco Heating System 2.2. A Comparison with Continued Combustible Cigarette Use or Smoking Abstinence [Poland]
C Haziza, G de La Bourdonnaye, P Picavet, G Baker, D Skiada, J Ancerewicz, K Jarus-Dziedzic*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
November 10, 2015
Heated Tobacco Products
Reduced exposure to harmful and potentially harmful constituents after 90 days of use of tobacco heating system 2.2 menthol in the U.S.: a comparison with continued cigarette use or smoking abstinence
C Haziza, G de La Bourdonnaye, P Picavet, G Baker, D Skiada, S Merlet, M Franzon, F Farmer, W Lewis, F Lüdicke
-
Poster
November 10, 2015
Reduced Exposure To Harmful And Potentially Harmful Constituents after 90 Days Of Use Of Tobacco Heating System 2.2 Menthol In Japan: A Comparison With Continued Cigarette Use Or Smoking Abstinence
C Haziza, N Lama, P Picavet, G Baker, J Ancerewicz, M Benzimra, M Franzon, M Endo*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
September 5, 2011
Reaction Pathways for the Pyrolysis of Glycerol, Propylene Glycol and Triacetin in the Gas Phase and at Solid Surfaces
C Tuma*, T Laino*, A Curioni*, E Jochnowitz, S Stolz
* This author is not affiliated with PMI. -
Poster
December 7, 2008
Quantifying the Level of Knowledge of Health Risks for New Tobacco Products: Development of a Measurement Certainty Index
G Kallischnigg, R Weitkunat, H Browne, M Smith, EB Sanders, R Dempsey, HJ Urban
-
Poster
August 29, 2013
Quantifying Perturbed Biological Processes By Analyzing High-Throughput Data Using Causal Networks Models
A Sewer, F Martin, TM Thomson, DM Vasilyev, J Park*, B Frushour, JW Westra*, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
September 21, 2013
Quantification Of The Effect Of Smoking And Smoking Cessation On Lipid Parameters: A Meta-Analysis
A van der Plas, G de La Bourdonnaye, G Baker, R Weitkunat, F Lüdicke
-
Poster
September 23, 2013
Quantification Of Biological Network Perturbations: Impact Assessment Using Causal Biological Network Models
F Martin, A Sewer, M Talikka, Y Xiang, Y Shen, J Hoeng, M Peitsch
-
Poster
July 12, 2016
Heated Tobacco Products
QSPR model development to simplify compound identification in complex matrix analysis
E Martin, P Pospisil
-
Poster
January 29, 2016
Platform 1
Proteomics Analysis of the Lung Proteome in Two Different Strains of Mice Within Systems Toxicology Approach for Product Assessment to Investigate Effects of Switching to Candidate and Prototype Modified Risk Tobacco Products, or To Smoking Cessation
A Elamin, B Titz, S Dijon, C Nury, T Schneider, F Martin, B Phillips, NV Ivanov, M Peitsch, J Hoeng
-
Poster
June 30, 2010
Priming and Oxidative Burst Induction in Human Peripheral Blood Neutrophils by Treatment with Cigarette Smoke
B Friedrichs, U Neumann, J Schueller
-
Poster
February 27, 2015
Population health impact model to estimate the effect of introducing modified risk tobacco products on mortality
Z Sponsiello Wang, PN Lee*, G Baker, A van der Plas, F Lüdicke, R Weitkunat
* This author is not affiliated with PMI. -
Poster
March 3, 2016
Population health impact model of introducing a reduced risk product: Initial estimate of the effective dose factor
F Martin, G Vuillaume, Z Sponsiello Wang, G Baker, F Lüdicke, R Weitkunat
-
Poster
October 6, 2004
Plasma Cotinine and Nicotine Metabolites in Urine, a Comparison of Caucasian and Japanese Smokers
C Martin Leroy, K Takada*, A R Tricker
* This author is not affiliated with PMI. -
Poster
March 23, 2015
Heated Tobacco Products
PK of Nicotine and Subjective Effects Following the Single Use of a Non-Menthol and Menthol Version of THS 2.2 in 2 Studies in Japan. A Comparison with Single Use of a Combustible Cigarette and Nicotine Gum
P Picavet, C Haziza, G Baker, N Lama, J Ancerewicz, M Benzimra, F Nobuoka*, M Sugimoto*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 4, 2014
Platform 1
Pharmacokinetics of nicotine following single use of a candidate modified risk tobacco product: the tobacco heating system 2.1
C Haziza, G Baker, J Ancerewicz, P Picavet, L Johnson, AJ Stewart*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Platform 1
Pharmacokinetics Of Nicotine And Subjective Effects Following The Single Use Of A Non-Menthol And Menthol Version Of Tobacco Heating System 2.2 In Two Studies In Japan: A Comparison With Single Use Of A Combustible Cigarette And Nicotine Gum
P Picavet, C Haziza, G Baker, N Lama, J Ancerewicz, M Benzimra, F Nobuoka*, M Sugimoto*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Heated Tobacco Products
Pharmacokinetics Of Nicotine And Subjective Effects Following The Single Use Of A Menthol Version Of Tobacco Heating System 2.2 In The US: A Comparison With Single Use Of A Combustible Cigarette And Nicotine Nasal Spray
C Haziza, G Baker, G de La Bourdonnaye, N Lama, J Ancerewicz, D Skiada, P Picavet, JL Borders*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
February 4, 2014
Perceived risks scale on use of tobacco and nicotine-containing products: Qualitative research findings
G Emilien, C Chrea, T Alfieri*, S Cano, N Mainy, T Salzberger, A Ramazzotti, F Lüdicke
* This author is not affiliated with PMI. -
Poster
October 5, 2011
Particle tracking in porous media to estimate aerosol filtration
L Ghazaryan*, DJ Lopez Penha, BJ Geurts*, S Stolz, A Kuczaj
* This author is not affiliated with PMI. -
Poster
November 2, 2005
PALM® Laser Microdissection and Pressure Catapulting (LMPC) Technology at the Department of Pathology at PMRL-G An Introduction to the Technology and its Application to Tissue Collection for Gene Expression Analyses of Different Mouse Tissues Using SuperA
H Weiler, S Gebel*, K Meurrens, B Gerstmayer*, A Bosio*
* This author is not affiliated with PMI. -
Poster
April 26, 2011
Organotypical epithelial 3D tissues (MatTek®) exposed in vitro to whole smoke as a potential alternative to rodent inhalation studies
D Weisensee, B Kurkowsky, M Hebestreit, S Wagner, J Schueller
-
Poster
September 20, 2013
Optimization Of Histological Processing Of Murine Lung Tissue
E Seow, B Phillips, E Veljkovic, P Vanscheeuwijck
-
Poster
June 9, 2016
Heated Tobacco Products
Non-targeted differential screening using LC-HRAM-MS as a tool for evaluating differences in chemical composition between samples and groups
D Arndt, A Knorr, M Bentley
-
Poster
December 3, 2006
Platform 1
Nicotine Bridging: A New Method to Extend Smoke Constituents Biomarker Measurements from Clinical Studies to Other Cigarette Mainstream Smoke Constituents
HJ Urban, MK Schorp*
* This author is not affiliated with PMI. -
Poster
June 9, 2016
Heated Tobacco Products
Non-targeted differential screening of complex matrices using GC×GC-TOFMS for comprehensive characterization of chemical composition and determination of significant differences
M Almstetter, A Knorr, Q Dutertre, F Martin, A Castellon, P Pospisil, M Bentley
-
Poster
September 20, 2010
New Computational Pipeline to Analyze Reverse Phase Protein Array Data from Adult Rats Exposed to Cigarette Smoke
Y Xiang, S Quadt-Humme, S Ansari, A Hengstermann*, J Hoeng, W Schlage
* This author is not affiliated with PMI. -
Poster
September 4, 2011
Multi-scale modeling of aerosol formation in pipe flow
C Winkelmann, A Kuczaj, S Stolz, BJ Geurts*
* This author is not affiliated with PMI. -
Poster
March 23, 2014
Multiplexed High Content Screening Analysis Reveals Reduced Toxicity Of A Prototypic Modified Risk Tobacco Product (pMRTP) As Compared To A Conventional Cigarette
I Gonzalez-Suarez, D Marescotti, S Acali, S Johne, D Goedertier, S Frentzel, C Mathis, AW Hayes, J Hoeng, M Peitsch
-
Poster
February 26, 2015
Molecular markers of early stage COPD in serum, sputum, and nasal epithelium from a case-control study
N Chaudhary, A Elamin, E Guedj, J Hoeng, NV Ivanov, K Luettich, P Leroy, F Martin, M Peitsch, A Sewer, M Talikka, B Titz, G Vuillaume
-
Poster
February 26, 2015
Modeling transport and evolution of aerosols for accurate predictions of local deposition in an in-vitro exposure system
A Kuczaj, M Nordlund, S Majeed, S Frentzel, M Peitsch, J Hoeng
-
Poster
November 9, 2014
Modeling of flow and evolving aerosol particles dynamics for computing local deposition in air-liquid interface experiments
A Kuczaj, M Nordlund, S Majeed, S Frentzel, J Hoeng, M Peitsch
-
Poster
February 26, 2011
Modeling Effective Properties of Porous Media Using Tomographic Reconstruction
DJ Lopez Penha, BJ Geurts*, S Stolz, JGM Kuerten*, M Nordlund, A Kuczaj
* This author is not affiliated with PMI. -
Poster
March 23, 2015
Mechanistic Network Models In Safety And Toxicity Evaluation Of Nutraceuticals
I Gonzalez-Suarez, D Marescotti, S Acali, S Johne, F Martin, R Dulize, K Baumer, D Peric, E Guedj, S Frentzel, C Mathis, NV Ivanov, J Hoeng, M Peitsch
-
Poster
March 18, 2014
Lung Sphingolipidome In A Mouse Model Of Cigarette Smoke-Induced Emphysema
-
Poster
September 24, 2005
Lung Inflammation In Rats After Acute Exposure To Cigarette Smoke
P Vanscheeuwijck, E Van Miert, B Friedrichs
-
Poster
January 9, 2016
Platform 1
Long term exposure to cigarette smoke impacts genes involved in cardiac muscle structure and function in Apoe-/- mouse while exposure to a candidate modified risk tobacco product, the Tobacco Heating System 2.2 (THS 2.2) aerosol does not
J Szostak, S Boue, M Talikka, E Guedj, F Martin, B Phillips, NV Ivanov, M Peitsch, J Hoeng
-
Poster
September 29, 2013
Ionic Liquid GCxGC-TOF-MS Approach For Generic Screening Of Aerosol Constituents In Aqueous Tobacco Aerosol Fractions And Analysis Of Microsomal Incubates
Q Dutertre, A Knorr, A Debrick , M Almstetter, F Martin, M Bentley
-
Poster
November 17, 2004
Involvement Of Semiquinone Radicals Generated From Dihydroxybenzenes In The In Vitro Cytotoxicity Of Cigarette Smoke Tar
S Chouchane, BP Muller*, A Wittig, FJ Tewes, JB Wooten
* This author is not affiliated with PMI. -
Poster
February 28, 2015
Platform 1
Investigation on puffing topography parameters and product evaluation recorded during five days of use of the Tobacco Heating System 2.2: A comparison with continued combustible cigarette use
G de La Bourdonnaye, T Bachmann, C Haziza, P Picavet, G Baker, D Skiada, K Jarus-Dziedzic*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
September 11, 2005
Initial Data On The Effects Of Long-Term Cigarette Mainstream Smoke Exposure And High Fat Diet On Apolipoprotein E-Deficient Mice
S Lebrun, W Stinn, H Weiler, P Kuhl*, B Friedrichs, HJ Urban, K Von Holt, T Wallerath, R Schleef*
* This author is not affiliated with PMI. -
Poster
September 20, 2006
Inflammatory And Epithelial Changes In Lungs From Apolipoprotein E Deficient Mice After Chronic Cigarette Mainstream Smoke Exposure
S Lebrun, W Stinn, H Weiler, B Friedrichs, A Buettner*, K Von Holt, T Wallerath, R Schleef*, HJ Haussmann
* This author is not affiliated with PMI. -
Poster
March 3, 2016
Heated Tobacco Products
Indoor Air Chemistry: An exploratory study on e-cigarette shows no negative impact on indoor air quality
M Gilchrist, C Goujon-Ginglinger, M Mitova, N Mottier, E G R Rouget, M Smith, S Maeder
-
Poster
March 23, 2015
Heated Tobacco Products
Indoor Air Chemistry. Comparative study between conventional cigarette and heat-not-burn technology
C Goujon-Ginglinger, P B Campelos, S Maeder, M Mitova, N Mottier, E G R Rouget, M Tharin, A R Tricker, M Smith
-
Poster
November 10, 2015
Heated Tobacco Products
Indoor Air Chemistry Assessment of environmental aerosol generated by Tobacco Heating System 2.2.
M Mitova, P B Campelos, C Goujon-Ginglinger, S Maeder, N Mottier, E G R Rouget, M Tharin, M Smith, A R Tricker
-
Poster
June 17, 2016
Platform 4
INDOOR AIR CHEMISTRY- An Exploratory Study On E-Cigarettes Shows No Negative Impact On Indoor Air Quality
C Goujon-Ginglinger, M Mitova, N Mottier, E G R Rouget, M Smith, M Tharin, S Maeder
-
Poster
February 28, 2015
Heated Tobacco Products
Indoor Air Chemistry (IAC) - Comparative Study Between Conventional Cigarette And Heat-Not-Burn Technology
-
Poster
September 7, 2016
Platform 4
Indoor air chemistry - An exploratory study on e-cigarette shows no negative impact on indoor air quality
M Smith, C Goujon-Ginglinger, M Mitova, S Maeder, N Mottier, E G R Rouget, M Tharin
-
Poster
January 16, 2014
Platform 2
In Vitro Toxicological Assessment Of Total Particulate Matter Of Tobacco Smoke And A pMRTP Aerosol In Human Lung Epithelial And Coronary Endothelial Cells
D Marescotti, I Gonzalez-Suarez, S Acali, S Johne, C Mathis, S Frentzel, P Walker*, S Ellis*, H Woodhouse*, H De Leon, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
January 12, 2016
Nicotine-Containing E-Vapor Products
In Vitro Test Systems for Aerosols Toxicology Assessment - Characterization of Exposure, Metabolism and Kinetics
A Knorr, Q Dutertre, S Majeed, C Mathis, S Frentzel, M Bentley, J Hoeng, P Vanscheeuwijck
-
Poster
March 6, 2011
In Vitro Exposure Of Organotypical 3d Epithelial Tissues To Cigarette Smoke As A Potential Alternative To Rodent Inhalation Studies
D Weisensee, B Kurkowsky, M Hebestreit, S Wagner, J Schueller
-
Poster
September 1, 2013
In Vitro Evaluation Of The Biological Impact Of Harmful And Potentially Harmful Constituents Of Tobacco Smoke Using A Systems Toxicology Approach
I Gonzalez-Suarez, C Mathis, E Guedj, P Walker*, S Ellis*, H Woodhouse*, R Dulize, K Baumer, D Peric, S Wagner, F Martin, NV Ivanov, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
June 20, 2010
Impact Of Cigarette Smoke On No Bioavailability In Endothelial Cells: Role Of Vascular NADPH Oxidase
Y Steffen, K Landwher, T Schwede*, K Stolle, M Lietz, S Wagner, M Moehring, S Lebrun, T Wallerath
* This author is not affiliated with PMI. -
Poster
June 8, 2007
Identification Of Causal Structures In Simulated Epidemiologic Data
Z Sponsiello Wang, R Weitkunat, E Kaelin, G Kallischnigg
-
Poster
June 19, 2007
Identification Of Causal Structures In Epidemiologic Data
Z Sponsiello Wang, R Weitkunat, G Kallischnigg
-
Poster
February 26, 2015
Platform 1
Human 3D Organotypic Nasal Epithelial Tissue Culture As An In Vitro Model To Evaluate Effects Of Cigarette Smoke Of A Candidate Modified Risk Tobacco Product: The Tobacco Heating System 2.2
C Mathis, M Cabanski, J Hoeng, S Frentzel, D Kuehn, S Majeed, C Merg, A Elamin, E Guedj, R Dulize, D Peric, K Trivedi, A Benyagoub, Y Xiang, F Martin, NV Ivanov, M Peitsch
-
Poster
March 3, 2016
Platform 1
How Do Consumers Use the Candidate MRTP Tobacco Heating System (THS): Analysis of Whole Offer Test Data from Five Countries
S Roulet, PP Magnani, G Kallischnigg, S Badoglio, K Ackermann, M Veit, A Ramazzotti
-
Poster
June 3, 2016
Heated Tobacco Products
High resolution mass spectrometric data analysis using Progenesis QI software for non-targeted screening (NTS)
S Della Gatta, C Buchholz, M Bentley, D Arndt
-
Poster
March 3, 2016
High Content Screening Assessment of Nicotine Toxicity in Primary Human Bronchial Epithelial Cells
I Gonzalez-Suarez, D Marescotti, S Acali, C Mathis, S Frentzel, J Hoeng, M Peitsch
-
Poster
November 9, 2014
High Content Screening analysis of the Biological Impact of Harmful / Potentially Harmful Constituents of Tobacco Smoke
I Gonzalez-Suarez, D Marescotti, S Acali, S Johne, F Martin, R Dulize, K Baumer, D Peric, E Guedj, S Frentzel, C Mathis, NV Ivanov, J Hoeng, M Peitsch
-
Poster
September 7, 2016
Nicotine-Containing E-Vapor Products
High Content Screening (HCS) approach to characterize phenotypic changes occurring during long-term treatment of human bronchial epithelial cells with cigarette smoke total particulate matter
D Marescotti, M Van der Toorn, A Laurent, K Luettich, S Frentzel, M Peitsch, J Hoeng
-
Poster
March 7, 2011
Genotoxicity Of The Gas/Vapor Phase (Gvp) Of Cigarette Mainstream Smoke In The Mouse Lymphoma Tk Assay (Mla)
S Wittke, E Trelles-Sticken
-
Poster
September 7, 2016
Heated Tobacco Products
Genomic analysis of L5178Y tk+/- cells and their induced tk-/- mutant colonies
JND Battey, D Smart, N Sierro, D McHugh, P Vanscheeuwijck, M Peitsch, NV Ivanov
-
Poster
July 12, 2008
From smoke to disease risk modelling. An integrated approach for risk assessment of potential reduced-risk tobacco products
C Martin Leroy, J Hoeng, H Browne, K Birthistle, R Dempsey, G Kallischnigg, M Smith, EB Sanders
-
Poster
March 14, 2012
Nicotine-Containing E-Vapor Products
Formaldehyde-Glycerol Hemiacetal - Absence of “Hidden” Formaldehyde in THS 2.2. Aerosols
A Knorr, L Gautier, A Debrick , E Tekeste, C Buchholz, M Almstetter, D Arndt, M Bentley
-
Poster
March 3, 2016
Nicotine-Containing E-Vapor Products
Final Psychometric Evaluation and Cultural Adaptation of the Perceived Risk Instrument (PRI) to Measure Perceived Risks Associated with the Use of Tobacco and Nicotine-Containing Products
C Chrea, G Emilien, T Salzberger, S Cano, T Alfieri*, N Mainy, A Ramazzotti, R Weitkunat, F Lüdicke
* This author is not affiliated with PMI. -
Poster
November 7, 2015
Factors Influencing Consumers’ Perceived Risk of Tobacco Products
MJ Atkinson*, C Chrea, T Salzberger, S Cano, G Emilien, N Mainy, A Ramazzotti, R Weitkunat, F Lüdicke, T Alfieri*
* This author is not affiliated with PMI. -
Poster
September 13, 2010
Evidence on Smoking and Chronic Obstructive Pulmonary Disease
BA Forey*, PN Lee*, N Lama, Z Sponsiello Wang, R Weitkunat
* This author is not affiliated with PMI. -
Poster
October 9, 2011
Platform 1
Evaluation of the diagnostic accuracy of a candidate biomarker to detect use of conventional cigarettes in users of tobacco products that do not burn tobacco
C Haziza, C Martin Leroy, M Stueber, D Lindner, N Forte, J Magnette
-
Poster
September 7, 2016
Heated Tobacco Products
Evaluation of the candidate modified risk tobacco product THS2.2 in a battery of in vitro genotoxicity and cytotoxicity tests
D McHugh, G Cudazzo, D Smart, D Keller*, P Vanscheeuwijck
* This author is not affiliated with PMI. -
Poster
September 14, 2009
Evaluation of Cardiovascular‐Disease‐Related Biomarkers in Adult Japanese Smokers and Non‐Smokers
C Haziza, T Humboldt*
* This author is not affiliated with PMI. -
Poster
March 3, 2016
Establishing a Valid Model to Estimate the Impact of Introducing a Reduced Risk Product on the Population as a Whole
G Baker, Z Sponsiello Wang, PN Lee*, JS Fry*, F Lüdicke, R Weitkunat
* This author is not affiliated with PMI. -
Publication
March 14, 2016
Heated Tobacco Products
Effects on the ApoE-/- mouse lung epigenome of exposure to a candidate modified risk tobacco product, THS 2.2, compared with conventional cigarettes
-
Poster
February 24, 2009
Effects of nicotine on vasomotor function of rat aortic rings in vitro
K Stolle, S Lebrun, T Wallerath
-
Poster
June 9, 2016
Platform 1
Effects of Cigarette Smoke, Cessation and Switching to Aerosol from Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in Two Mouse Strains
T Schneider, B Titz, S Boue, B Phillips, M Talikka, T Vihervaara*, C Nury, A Elamin, E Guedj, M Peck, W Schlage, M Cabanski, P Leroy, G Vuillaume, F Martin, NV Ivanov, E Veljkovic, K Ekroos*, R Laaksonen, P Vanscheeuwijck, M Peitsch, J Hoeng
* This author is not affiliated with PMI. -
Poster
March 17, 2014
Effects Of Cigarette Smoke On The High Fat Diet-Induced ApoE-/- Mouse Model Of Diabetic Atherosclerosis
D Sharma, A Iskandar, B Phillips, H De Leon, E Veljkovic, M Cabanski, J Hoeng, M Peitsch
-
Poster
November 9, 2014
Effects of Cigarette Smoke Exposure on the Insulin Resistance-Related Metabolic Changes in the High Fat Diet-fed ApoE Knock-Out Mice
A Iskandar, D Sharma, S Boue, H De Leon, B Phillips, M Cabanski, E Veljkovic, NV Ivanov, J Hoeng, M Peitsch
-
Poster
September 12, 2011
Effectiveness of the in vitro Comet assay in the determination of cigarette smoke effects in human lung epithelial cells in conjunction with an air-liquid interface exposure system
S Weber, M Hebestreit, T Wilms, B Kurkowsky, T Meisgen
-
Poster
June 18, 2013
Platform 1
Effectiveness Of Smoking Cessation Methods Among Chinese Smokers: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials
S Shi*, S Huang*, H Xu, C Lin*, R Weitkunat, G Baker, Z Sponsiello Wang
* This author is not affiliated with PMI. -
Poster
October 24, 2005
Development of two different methods to characterize the chemical composition of cigarette mainstream smoke
N Plata, I Hofer, S Roudier, JP Schaller
-
Poster
March 16, 2016
Heated Tobacco Products
Development of a Primary Cell-Based Model of the Human Alveolar Epithelium
S Steiner, D Marescotti, S Acali, S Frentzel, C Mathis, K Luettich, J Hoeng
-
Poster
August 18, 2014
Development of a New Instrument to Measure Perceived Risks Associated with The Use of Tobacco and Nicotine-Containing Products
G Emilien, C Chrea, T Alfieri*, S Cano, N Mainy, T Salzberger, A Ramazzotti, R Weitkunat, F Lüdicke
* This author is not affiliated with PMI. -
Poster
November 2, 2005
Detection of CD4+ and CD8+ T-Lymphocytes in Lung Tissue of A/J-Mice by Immunohistology
A Buettner*, S Toeller, T Gruen, H Weiler
* This author is not affiliated with PMI. -
Poster
April 7, 2013
CSEO – The Cigarette Smoke Exposure Ontology
S Ansari, E Younesi*, M Guendel*, S Ahmadi*, C Coggins*, J Hoeng, M Hofmann-Apitius*, M Peitsch
* This author is not affiliated with PMI. -
Poster
June 12, 2013
Crowd-Verification Of Systems Biology Research Challenges: Species Translation And Biological Networks
E Bilal*, J Binder, S Boue, B Fields*, AW Hayes, A Iskandar, R Kleiman*, P Meyer*, R Norel*, J Park*, C Poussin, K Rhrissorrakrai*, JJ Rice*, J Sprengel*, G Stolovitzky, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
March 7, 2011
Correlative Histopathology and Systems Biology Approach in Product Risk Assessment
W Schlage, S Ansari, Y Xiang, S Quadt-Humme, U Kogel, S Gebel*, A Hengstermann*, J Hoeng, M Peitsch, A Buettner*, K Meurrens
* This author is not affiliated with PMI. -
Poster
March 7, 2013
Contribution of single smoke constituents to the mutagenic activity of the gas/vapor phase of cigarette mainstream smoke
S Weber, T Meisgen, J Diekmann, A Wittig, K Rustemeier
-
Poster
June 27, 2011
Computer‐Assisted Structure Identification: Predictive Models and Automation
A Monge, A Knorr, M Stueber, D Arndt, A Stratmann, E Martin, M Peitsch, NV Ivanov, P Pospisil
-
Poster
November 9, 2014
Comparison of the biological impact of cigarette smoke and a prototypic modified risk tobacco product on human versus rat primary normal bronchial epithelial cells
U Kogel, C Poussin, DE Messinis *, S Frentzel, I Gonzalez-Suarez, F Martin, C Mathis, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
April 27, 2009
Comparison of Exposure to Selected Cigarette Smoke Constituents of Adult Smokers and Non-smokers in a European Multi-centre, Observational Study
D Lindner, C Martin Leroy, M Smith, J Magnette, C Haziza, A R Tricker
-
Poster
September 6, 2010
Comparison of Biomarkers of Exposure to Smoke Constituents in Japanese Smokers
D Lindner, C Martin Leroy, A R Tricker
-
Poster
June 17, 2016
Heated Tobacco Products
Comparing The Levels Of Harmful Compounds In Smokers That Either Continue To Smoke, Quit Or Switch To THS2.2 Menthol (USA)
C Haziza, G de La Bourdonnaye, P Picavet, G Baker, D Skiada, S Merlet, M Franzon, F Farmer, W Lewis, F Lüdicke
-
Poster
June 17, 2016
Heated Tobacco Products
Comparing the Levels of Harmful Compounds in Smokers that either Continue to Smoke, Quit or Switch to THS2.2 Menthol (Japan)
C Haziza, N Lama, A Donelli, P Picavet, G Baker, J Ancerewicz, M Benzimra, M Franzon, M Endo*, F Lüdicke
* This author is not affiliated with PMI. -
Poster
July 12, 2016
Heated Tobacco Products
Community-Reviewed Biological Network Models for Toxicology and Drug Discovery Applications
SBV Improver*
* This author is not affiliated with PMI. -
Poster
May 1, 2016
Heated Tobacco Products
Cilia of human MucilAirTM are Less Impacted by the Exposure to the Aerosol Candidate-Modified Risk Tobacco Product than to Whole Smoke from Conventional Cigarettes In Vitro
S Frentzel, D Grandolfo, D Kuehn, S Majeed, P Leroy, M Peitsch, J Hoeng
-
Poster
November 10, 2015
Heated Tobacco Products
Cilia of human MucilAir (TM) are less impacted by the exposure to the aerosol of a candidate modified risk tobacco product than to whole smoke from conventional cigarettes in vitro
-
Poster
February 9, 2009
Cigarette-Smoke-Induced Phenotype in Nrf2 KO Mice
J Schueller, T Mueller
-
Poster
March 7, 2010
Cigarette‐smoke‐induced cellular transformation in vitro using the Bhas 42 cell transformation assay
D Weisensee, J Schueller
-
Poster
March 6, 2011
Cigarette‐smoke‐dependent changes in the respiratory and cardiovascular system of spontaneously hypertensive (SH) rats and the effect of smoking cessation
A Berges, B Friedrichs, I Gallitz, S Quadt-Humme, Y Steffen, K Stolle, S Lebrun, M Lietz
-
Poster
March 23, 2014
Cigarette smoke-induced perturbations of molecular pathways in human organotypic cultures of buccal and gingival mucosa
M Cabanski, C Mathis, A Iskandar, R Kostadinova, S Frentzel, D Kuehn, S Majeed, M Geertz, F Talamo, E Guedj, Y Xiang, F Martin, W Schlage, AW Hayes, M Peitsch, J Hoeng
-
Poster
October 20, 2010
Cigarette smoke increases the adhesion of human monocytes to endothelial cells
M Lietz, C Berger, HP Lammerich, Y Steffen, K Stolle, S Lebrun, J Schueller, T Wallerath
-
Poster
February 12, 2010
Cigarette Smoke Enhances Foam Cell Formation Independent of Scavenger Receptor Gene Expression
K Stolle, Y Steffen, S Lebrun
-
Poster
February 24, 2009
Cigarette smoke enhances abdominal aortic aneurysm formation in angiotensin II-treated Apolipoprotein E-deficient mice
K Stolle, A Berges, M Lietz, S Lebrun, R Schleef*, T Wallerath
* This author is not affiliated with PMI. -
Poster
October 5, 2008
Cigarette Smoke and High Fat/High Cholesterol Diet Induce Atherogenesis in Apolipoproteine-Deficient Mice by Different Pathways
K Stolle, S Ansari, A Berges, M Lietz, S Lebrun, R Schleef*, T Wallerath
* This author is not affiliated with PMI. -
Poster
March 16, 2016
Heated Tobacco Products
Chronological Changes in BEAS-2B Cells Chronically Exposed to Cigarette Smoke to Total Particulate Matter
M Van der Toorn, D Marescotti, S Johne, C Merg, J Hoeng, M Peitsch, K Luettich
-
Poster
March 23, 2015
Characterization of the Vitrocell 24/48 in vitro exposure system using mainstream cigarette smoke
S Frentzel, S Majeed, D Kuehn, P Leroy, P Guy, A Knorr, A Kuczaj, M Nordlund, J Hoeng, M Peitsch
-
Poster
November 9, 2009
Characterization of Strain A Mice as a Potential Model for Lung Emphysema
E Van Miert, B Friedrichs, H Weiler, J Pype, M Peck, P Vanscheeuwijck
-
Poster
September 1, 2013
Characterization Of An In Vitro Whole Cigarette Smoke Exposure System (VITROCELL® 24/48)
S Majeed, S Wagner, S Frentzel, D Kuehn, D Goedertier, M Peitsch, J Hoeng, P Vanscheeuwijck
-
Poster
June 5, 2016
Characterization of Aerosol Exposure, Metabolism and Pharmacokinetics for ToxicoLogical Assessment Using In Vitro Organotypical Airway Models
A Knorr, Q Dutertre, M Rhouma, E Martin, M Almstetter, S Majeed, C Mathis, S Frentzel, M Bentley, J Hoeng, P Vanscheeuwijck, M Peitsch
-
Poster
May 20, 2016
Characterization of a system used to expose organ like tissues to aerosols a bayesian analysis of a split split plot design
S Kleinhans, G Vuillaume, S Steiner, G Kratzer, S Majeed, S Frentzel, F Martin, J Hoeng
-
Poster
January 29, 2016
Heated Tobacco Products
BELIEF: A semi-automated curation tool to build mechanisitc
J Szostak, S Ansari, M Talikka, J Fluck*, S Madan*, F Martin, M Peitsch, J Hoeng
* This author is not affiliated with PMI. -
Poster
June 20, 2014
Heated Tobacco Products
Association of urinary 11-dehydro-thromboxane b2 levels in smoking, smoking cessation and tobacco heating system use
A van der Plas, S Pouly, G de La Bourdonnaye, G Baker, F Lüdicke
-
Poster
November 10, 2015
Heated Tobacco Products
Assessment of the Tobacco Heating System 2.2, a candidate Modified Risk Tobacco Product, on human organotypic nasal and bronchial epithelial tissue culture using systems toxicology approach
F Zanetti, A Iskandar, C Mathis, M Cabanski, S Johne, D Kuehn, S Majeed, C Merg, A Elamin, E Guedj, R Dulize, D Peric, K Trivedi, A Benyagoub, Y Xiang, F Martin, P Leroy, S Frentzel, NV Ivanov, M Peitsch
-
Poster
September 11, 2015
Application of the HMOX1 Promoter/Enhancer Assay for Routine Determination of Cellular Stress Induced by Cigarette Smoke
A Knorr, S Gebel*, T Mueller
* This author is not affiliated with PMI. -
Poster
March 23, 2015
Heated Tobacco Products
Application of Systems Pharmacology to Identify Exposure Response Markers in Peripheral Blood After Switching to a Candidate Modified Risk Tobacco Product: the Tobacco Heating System 2.1 (THS 2.1)
F Martin, M Talikka, C Haziza, J Ancerewicz, J Hoeng, M Peitsch
-
Poster
August 12, 2010
Application of A Dynamic Model of ApoE-/- Mouse Atherosclerosis to Assess the Impact of Cigarette Smoke Exposure on Endothelial Cell Function
A Berges, Y Cheng, C Haziza, J Hoeng, S Lebrun, RB Lichtner, M Lietz, W Schlage, M Peitsch
-
Poster
September 29, 2013
Application of A Dynamic Model of ApoE-/- Mouse Atherosclerosis to Assess the Impact of Cigarette Smoke Exposure on Endothelial Cell Function
JND Battey, N Sierro, NV Ivanov
-
Poster
September 29, 2013
Applicability Of Different Soft Nucleophiles For Screening Reactive Metabolites Resulting From Microsomal Activation Of Furan Mixtures And Cigarette Smoke
JND Battey, N Sierro, NV Ivanov
-
Poster
April 25, 2009
Analysis of inflammatory markers in adult Japanese smokers and non-smokers
C Martin Leroy, J Oey, D Lindner, C Haziza, M Peck, J Magnette
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Poster
September 1, 2013
An OpenFOAM®-Based Tool For Computational Modeling Of Aerosol Nucleation And Transport
EM Frederix*, A Kuczaj, M Nordlund, C Winkelmann, I Zinovik, BJ Geurts*
* This author is not affiliated with PMI. -
Poster
February 15, 2015
An Impact Assessment of Combustible Cigarette Smoke Exposure on Organotypic Models of Bronchial Epithelial Mono-culture and Bronchial Epithelial/Fibroblast Co-culture
A Iskandar, Y Xiang, S Frentzel, C Mathis, P Leroy, S Majeed, D Kuehn, F Martin, M Talikka, M Peitsch, J Hoeng
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Poster
September 20, 2006
An Exploratory Inhalation Toxicity Study with Cigarette Mainstream Smoke in Two Transgenic Mouse Strains, rasH2 and p53+/-
P Vanscheeuwijck, K Meurrens, J Arts*, E Duistermaat*, CF Kuper, P Terpstra*
* This author is not affiliated with PMI. -
Poster
July 24, 2016
Heated Tobacco Products
An Efficient Global Optimization Python Module based on Generalized Simulating Annealing: PyGenSA
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Poster
November 10, 2015
Heated Tobacco Products
Aerosol from a candidate modified risk tobacco product has reduced effects on chemotaxis and transendothelial migration compared to smoke from conventional cigarettes
M Van der Toorn, S Frentzel, H De Leon, D Goedertier, M Peitsch, J Hoeng
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Poster
June 24, 2016
Heated Tobacco Products
Accuracy of the Smoking Questionnaire (SQ)
Z Sponsiello Wang, G de La Bourdonnaye, M David, G Baker, F Lüdicke, R Weitkunat
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Poster
March 5, 2014
A Web Platform For Verification Of Biological Network Models In The Age Of Collaborative-Competition
S Ansari, DF Anseimo *, J Binder, S Boue, AW Hayes, J Hoeng, A Iskandar, R Kleiman*, R Norel*, B O'Neel, M Peitsch, C Poussin, D Pratt*, K Rhrissorrakrai*, W Schlage, G Stolovitzky, M Talikka
* This author is not affiliated with PMI. -
Poster
April 27, 2009
Platform 1
A One-month Study to Evaluate Biomarkers of Exposure and Effect in Smokers Switching from Conventional Cigarettes to an Electrically Heated Cigarette Smoking System
C Martin Leroy, K Jarus-Dziedzic*, J Ancerewicz, M Bentley, H Browne
* This author is not affiliated with PMI. -
Poster
July 17, 2011
A Novel Reverse Engineering Method for Gene/Protein Network Reconstruction ‐ Divergence Weighted Independence Graphs
Y Xiang, M Talikka, V Belcastro, P Sperisen, J Hoeng, J Whittaker*
* This author is not affiliated with PMI. -
Poster
October 14, 2011
A multifactorial integrative analysis scheme for combined mRNA and microRNA expression datasets
A Sewer, V Belcastro, A Hengstermann*, C Mathis, J Hoeng
* This author is not affiliated with PMI. -
Poster
August 26, 2016
A multi-analyte method using liquid chromatography with high resolution accurate mass spectrometry for the determination of aerosol constituents in 3D tissue cultures
Q Dutertre, A Knorr, M Rhouma, S Majeed, M Bentley
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Poster
August 28, 2011
A Modular Cell-Type Focused Inflammatory Process Network Model for Non-diseased Pulmonary Tissue
A Hengstermann*, S Gebel*, W Schlage, JW Westra*, C Mathis, TM Thomson, B Wong*, V Hoang*, E Veljkovic, BP Muller*, M Peck, RB Lichtner, R Deehan*, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
October 5, 2014
Platform 2
A Mechanistic Study Using 2D-Page Proteomic Approach To Investigate The Effect Of Cigarette Smoke-Induced COPD, Cessation And Switching To Modified Risk Tobacco Product In The Lungs of C57bl/6 Mice
S Dijon, T Schneider, A Elamin, E Veljkovic, B Phillips, B Titz, F Martin, NV Ivanov, J Hoeng, M Peitsch
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Poster
March 23, 2014
Platform 2
A Mechanistic Study Of Cigarette Smoke-Induced COPD In C57BL/6 Mice: The Impact Of Switching To pMRTP
E Veljkovic, B Phillips, M Peck, A Buettner*, G Vuillaume, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
March 23, 2015
Platform 2
A Mechanistic Study of Cigarette Smoke-Induced COPD in C57BL/6 Mice: The changes in lung epigenome following smoking cessation or switching to aerosol from a prototypic modified risk
N Sierro, M Talikka, J Hoeng, M Peitsch, AW Hayes, NV Ivanov
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Publication
June 30, 2013
Platform 2
A Mechanistic Study Of Cigarette Smoke-Induced COPD In C57bl/6 Mice And The Effects Of Cessation Or Switching To A pMRTP Aerosol
B Phillips, E Veljkovic, M Talikka, F Martin, NV Ivanov, M Peck, A Buettner*, J Hoeng, G Vuillaume, M Peitsch
* This author is not affiliated with PMI. -
Poster
June 30, 2013
A Mechanistic Study Of Cigarette Smoke-Induced COPD And Cessation Effects In C57bl/6 Mice
B Phillips, E Veljkovic, M Peck, A Buettner*, G Vuillaume
* This author is not affiliated with PMI. -
Poster
June 16, 2013
A Highly Sensitive Method For The Quantification Of Key Oxysterols In Plasma Using Liquid Chromatography With High Resolution Mass Spectrometry
S Della Gatta, D Arndt, M Bentley
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Presentation
August 28, 2011
Heated Tobacco Products
A graph theoretic method for assessing topological perturbations in Biological Networks
F Martin, A Sewer, TM Thomson, DA Drubin*, D Pratt*, AL Matthews*, R Kleiman*, D de Graaf*, J Hoeng, M Peitsch
* This author is not affiliated with PMI. -
Poster
June 23, 2010
3D‐Pictogram of Risk Measures in Epidemiology
E Kaelin, P Sperisen
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Presentation
October 24, 2005
Biochemical, immunohistochemical, and molecular biomarkers in rats following inhalation of cigarette mainstream smoke (MS) or a mixture of cigarette sidestream smoke (SS) and MS
D Weisensee, R Kindt, E Van Miert, R Stabbert, G Schepers, W Schlage, HJ Haussmann
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Presentation
December 3, 2006
A Combined Frequentist-Bayesian Approach to Risk Quantification
HJ Urban, AP Brown*, R Dempsey, G Kallischnigg, M Peck, EB Sanders, P Vanscheeuwijck, R Weitkunat
* This author is not affiliated with PMI. -
Presentation
November 9, 2008
Pulmonary Neoplasia in Strain A Mice following Long-Term Tobacco Smoke Inhalation
RB Lichtner, A Buettner*, S Gebel*, F van Overveld, HJ Haussmann, W Stinn
* This author is not affiliated with PMI. -
Presentation
February 9, 2009
From Cellular Genotype to Cigarette Smoke-Induced Phenotype: The Case of Nrf2
T Mueller, J Schueller
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Presentation
October 9, 2013
Verification Of Systems Biology Research In The Age Of Collaborative-Competition
J Hoeng, N Chaudhary, M Talikka, S Boue, G Stolovitzky, M Peitsch, J Sprengel*, R Kleiman*, AW Hayes, B Fields*, J Park*, E Bilal*, K Rhrissorrakrai*, JJ Rice*, R Norel*, P Meyer*, A Iskandar, V Belcastro, J Binder
* This author is not affiliated with PMI. -
Presentation
July 21, 2013
Verification Of Systems Biology Research In The Age Of Collaborative- Competition
J Hoeng, J Binder,